Enhancement of Regression of Cervical Intraepithelial Neoplasia II (Moderate Dysplasia) With Topically Applied All-trans-Retinoic Acid: a Randomized Trial

Background Retinoids enhance differentiation of most epithelial tissues. Epidemiologic studies have shown an inverse relationship between dietary intake or serum levels of vitamin A and the development of cervical dysplasia and/or cervical cancer. Pilot and phase I investigations demostrated the fea...

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Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 1994-04, Vol.86 (7), p.539-543
Hauptverfasser:	Meyskens, Frank L., Surwit, Earl, Moon, Thomas E., Childers, Joel M., Davis, John R., Dorr, Robert T., Johnson, Cynthia S., Alberts, David S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intravaginal Adult Antineoplastic agents Antineoplastic Agents - administration & dosage Antineoplastic Agents - adverse effects Antineoplastic Agents - therapeutic use Biological and medical sciences Biopsy Cervical cancer Cervical Intraepithelial Neoplasia - drug therapy Cervical Intraepithelial Neoplasia - pathology Chemotherapy Drug therapy Female Humans Logistic Models Medical research Medical sciences Pharmacology. Drug treatments Remission Induction Tretinoin - administration & dosage Tretinoin - adverse effects Tretinoin - therapeutic use Uterine Cervical Neoplasms - drug therapy Uterine Cervical Neoplasms - pathology
Online-Zugang:	Volltext
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