Ag(I)-coordinated hairpin DNA for homogenous electronic monitoring of hepatitis C virus accompanying isothermal cycling signal amplification strategy

This work designs a new homogenous electronic monitoring platform for sensitive detection of hepatitis C virus (HCV) on an immobilization-free Ag(I)-assisted hairpin DNA through the cytosine–Ag+–cytosine coordination chemistry. The assay consists of target-induced Ag+ dissociation from hairpin DNA a...

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Veröffentlicht in:	Biosensors & bioelectronics 2015-11, Vol.73, p.195-201
Hauptverfasser:	Lu, Minghua, Xu, Linfang, Zhang, Xiaona, Xiao, Rui, Wang, Youmei
Format:	Artikel
Sprache:	eng
Schlagworte:	Ag(I)-coordinated hairpin DNA Biosensing Techniques - methods DNA Probes - chemistry DNA Probes - genetics Electrochemical DNA sensor Electrochemical Techniques - methods Hepacivirus - genetics Hepacivirus - isolation & purification Hepatitis C virus Homogeneous assay Humans Inverted Repeat Sequences Iodides Isothermal circular strand-displacement polymerization Reproducibility of Results RNA, Viral - blood RNA, Viral - genetics RNA, Viral - isolation & purification Silver Compounds
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