DLA-identical marrow grafts after low-dose total-body irradiation : addition of viable donor peripheral blood mononuclear cells does not enhance engraftment

Total-body irradiation (TBI)* (400 cGy) delivered at a dose rate of 7 cGy/min from opposing super(60)Co sources is marrow-lethal in dogs, with only 1 of 28 animals showing hematopoietic recovery and survival. In previous studies, we have used otherwise supralethal doses of TBI, 450, 600, 700, 800, a...

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Veröffentlicht in:	Transplantation 1995-05, Vol.59 (10), p.1481-1482
Hauptverfasser:	STORB, R, RAFF, R. F, DEEG, H. J, GRAHAM, T. C, SCHUENING, F. G, SHULMAN, H, BRYANT, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Bone Marrow Transplantation - immunology Dogs Dose-Response Relationship, Radiation Female Graft Survival Histocompatibility Antigens - analysis Leukocytes, Mononuclear - immunology Leukocytes, Mononuclear - radiation effects Male Medical sciences Radiation therapy and radiosensitizing agent Treatment with physical agents Treatment. General aspects Tumors Whole-Body Irradiation
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