Metabolic and Gonadotropic Impact of Sequential Obesogenic Insults in the Female: Influence of the Loss of Ovarian Secretion

The reproductive impact of persistent energy excess in the female remains incompletely defined, yet the escalating prevalence of obesity calls for better understanding of this phenomenon. Also along this line, the influence of ovarian hormones on the pathophysiology of obesity and its comorbidities...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2015-08, Vol.156 (8), p.2984-2998
Hauptverfasser:	Sánchez-Garrido, Miguel A, Ruiz-Pino, Francisco, Manfredi-Lozano, María, Leon, Silvia, Heras, Violeta, Castellano, Juan M, Castaño, Justo P, Luque, Raúl M, Vázquez, María J, Roa, Juan, Romero-Ruiz, Antonio, Diéguez, Carlos, Pinilla, Leonor, Tena-Sempere, Manuel
Format:	Artikel
Sprache:	eng
Schlagworte:	17β-Estradiol Aging - physiology Animals Arcuate nucleus Body weight Comorbidity Deregulation Diet, High-Fat - adverse effects Energy intake Female Females Glucose Glucose tolerance Gonadotrophs - metabolism Gonadotrophs - physiology Gonadotropins High fat diet Hormones Hypothalamus Insulin Kiss1 protein Leptin Luteinizing hormone Metabolism Nutritional Physiological Phenomena Obesity Obesity - etiology Obesity - metabolism Obesity - physiopathology Ovariectomy Ovaries Ovary - physiopathology Ovary - secretion Overnutrition Overnutrition - metabolism Overnutrition - physiopathology Overweight Pituitary (anterior) Rats Rats, Wistar Reproduction - physiology Secretions Sex hormones Weaning
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