Esophagus adenocarcinoma in a young patient with celiac disease; Is celiac disease a predisposing factor for esophagus adenocarcinoma as well as squamous cell carcinoma?

We report a 36-year-old female with longstanding oily diarrhea and new-onset dysphagia that was diagnosed as celiac disease and esophagus adenocarcinoma. Celiac is a multisystemic autoimmune disease associated with a longstanding inflammatory process, especially in the gastrointestinal tract. This c...

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Veröffentlicht in:Clinical journal of gastroenterology 2014-08, Vol.7 (4), p.324-327
Hauptverfasser: Mahmud, Baghbanian, Mohammadkazem, Amirbeigy, Hasan, Salmanroghani, Fariba, Binesh, Ali, Baghbanian, Mohamadreza, Zare-Khormizi
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container_end_page 327
container_issue 4
container_start_page 324
container_title Clinical journal of gastroenterology
container_volume 7
creator Mahmud, Baghbanian
Mohammadkazem, Amirbeigy
Hasan, Salmanroghani
Fariba, Binesh
Ali, Baghbanian
Mohamadreza, Zare-Khormizi
description We report a 36-year-old female with longstanding oily diarrhea and new-onset dysphagia that was diagnosed as celiac disease and esophagus adenocarcinoma. Celiac is a multisystemic autoimmune disease associated with a longstanding inflammatory process, especially in the gastrointestinal tract. This chronic inflammation may lead to a modest increase in neoplasia risk. There is a modest increased risk of malignancy in celiac disease, particularly adenocarcinoma and T-cell lymphoma of the small intestine and squamous cell carcinoma (SCC) of the esophagus, mouth, and pharynx. Although there is an association between SCC of the esophagus and celiac disease, there are no reports in the English literature about a relationship between celiac disease and esophageal adenocarcinoma. This case shows that as well as SCC, adenocarcinoma of the esophagus may also occur in patients with longstanding celiac disease.
doi_str_mv 10.1007/s12328-014-0509-z
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subjects Abdominal Surgery
Adenocarcinoma - etiology
Adult
Carcinoma, Squamous Cell - etiology
Case Report
Causality
Celiac Disease - complications
Colorectal Surgery
Esophageal Neoplasms - etiology
Female
Gastroenterology
Hepatology
Humans
Medicine
Medicine & Public Health
Surgical Oncology
title Esophagus adenocarcinoma in a young patient with celiac disease; Is celiac disease a predisposing factor for esophagus adenocarcinoma as well as squamous cell carcinoma?
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