From mouse to man: safety, immunogenicity and efficacy of a candidate leishmaniasis vaccine LEISH‐F3+GLA‐SE

Key antigens of Leishmania species identified in the context of host responses in Leishmania‐exposed individuals from disease‐endemic areas were prioritized for the development of a subunit vaccine against visceral leishmaniasis (VL), the most deadly form of leishmaniasis. Two Leishmania proteins—nu...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Clinical & translational immunology 2015-04, Vol.4 (4), p.e35-n/a
Hauptverfasser:	Coler, Rhea N, Duthie, Malcolm S, Hofmeyer, Kimberly A, Guderian, Jeffery, Jayashankar, Lakshmi, Vergara, Julie, Rolf, Tom, Misquith, Ayesha, Laurance, John D, Raman, Vanitha S, Bailor, H Remy, Cauwelaert, Natasha Dubois, Reed, Steven J, Vallur, Aarthy, Favila, Michelle, Orr, Mark T, Ashman, Jill, Ghosh, Prakash, Mondal, Dinesh, Reed, Steven G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Anorexia Antigens Blood Candidates CD4 antigen CD8 antigen Clinical trials Computer simulation Cytokines Emulsions Enzymes Fusion protein Hydrolase Immunogenicity Infections Interferon Leishmania Ligands Lipid A Lymphocytes T Major histocompatibility complex Methyltransferase Nanoemulsions Pain Parasites Parasitic diseases Proteins Sterols Studies Toll-like receptors Tropical diseases Tumor necrosis factor-TNF Vaccines Visceral leishmaniasis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!