HS-23, a Lonicera japonica extract, reverses sepsis-induced immunosuppression by inhibiting lymphocyte apoptosis

Lonicera japonica Thunberg, a widely used traditional Chinese medicine, possesses antibacterial, antiviral, and antiendotoxin activities. This study investigated the molecular mechanisms of HS-23, the ethanol extract of the dried flower buds of L. japonica, on sepsis-induced immunosuppression. Male...

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Veröffentlicht in:	Journal of ethnopharmacology 2015-08, Vol.171, p.231-239
Hauptverfasser:	Kim, So-Jin, Kim, Joon-Sung, Choi, Hyo-Sun, Kim, Young-Mok, Hong, Sung-Woon, Hum Yeon, Sung, Kim, Yeon, Lee, Sun-Mee
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis - drug effects CD4-Positive T-Lymphocytes - drug effects CD8-Positive T-Lymphocytes - drug effects Cytokines - immunology Immunosuppression Lonicera Lonicera japonica Lymphocyte apoptosis Male Mice, Inbred ICR Phytotherapy Plant Extracts - pharmacology Plant Extracts - therapeutic use Sepsis Sepsis - drug therapy Sepsis - immunology Spleen - cytology Spleen - drug effects Spleen - immunology Th1/Th2 cytokine
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