The Prognostic Impact of Tumor Size on Cancer-Specific and Overall Survival Among Patients With Pathologic T3a Renal Cell Carcinoma

Micro-Abstract One third of patients are currently diagnosed with locally advanced renal cell carcinoma (RCC). We evaluated the prognostic role of tumor dimension among patients with stage pT3a RCC. Patients with tumor size > 8 cm showed a 3.65-fold higher risk of cancer-specific mortality compar...

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Veröffentlicht in:	Clinical genitourinary cancer 2015-08, Vol.13 (4), p.e235-e241
Hauptverfasser:	Schiavina, Riccardo, Borghesi, Marco, Chessa, Francesco, Dababneh, Hussam, Bianchi, Lorenzo, Della Mora, Livia, Del Prete, Chiara, Longhi, Barbara, Rizzi, Simona, Fiorentino, Michelangelo, Martorana, Giuseppe, Brunocilla, Eugenio
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Carcinoma, Renal Cell - pathology Female Hematology, Oncology and Palliative Medicine Humans Kidney Neoplasms - pathology Locally advanced renal cell carcinoma Male Middle Aged Neoplasm Grading Prognosis Prospective Studies Radical nephrectomy Survival Survival Analysis TNM classification Tumor Burden Tumor dimension Urology
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Zusammenfassung:	Micro-Abstract One third of patients are currently diagnosed with locally advanced renal cell carcinoma (RCC). We evaluated the prognostic role of tumor dimension among patients with stage pT3a RCC. Patients with tumor size > 8 cm showed a 3.65-fold higher risk of cancer-specific mortality compared with those with a stage pT3a RCC tumor ≤ 8 cm ( P < .001). Tumor size should be taken into account in future revisions of the tumor, node, metastasis (TNM) staging system.
ISSN:	1558-7673 1938-0682
DOI:	10.1016/j.clgc.2014.06.011