Prostanoids as anti-inflammatory therapy: separating the good from the bad

Previous work has suggested that the bronchodilator properties of PGE2 in human airways are mediated via activation of the EP4 receptor, 5 whereas the undesirable triggering of airway sensory nerves appears to be mediated by the EP3 receptor. 6 An advantage of the study by Birrell et al is that they...

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