Effect of hyperoxic and hyperbaric conditions on the adenosinergic pathway and CD26 expression in rat

The nucleoside adenosine acts on the nervous and cardiovascular systems via the A2A receptor (A2AR). In response to oxygen level in tissues, adenosine plasma concentration is regulated in particular via its synthesis by CD73 and via its degradation by adenosine deaminase (ADA). The cell-surface endo...

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Veröffentlicht in:	Journal of applied physiology (1985) 2015-07, Vol.119 (2), p.140-147
Hauptverfasser:	Bruzzese, Laurie, Rostain, Jean-Claude, Née, Laëtitia, Condo, Jocelyne, Mottola, Giovanna, Adjriou, Nabil, Mercier, Laurence, Berge-Lefranc, Jean-Louis, Fromonot, Julien, Kipson, Nathalie, Lucciano, Michel, Durand-Gorde, Josée-Martine, Jammes, Yves, Guieu, Régis, Ruf, Jean, Fenouillet, Emmanuel
Format:	Artikel
Sprache:	eng
Schlagworte:	5'-Nucleotidase - genetics Adenosine - genetics Adenosine Deaminase - genetics Animals Cell Line Cyclic AMP - genetics Dipeptidyl Peptidase 4 - genetics Down-Regulation - genetics Effects Gene expression Hyperoxia - genetics Hypoxia Male Mice Oxidative stress Oxidative Stress - genetics Oxygen - metabolism Peptides Rats Rats, Sprague-Dawley Reactive Oxygen Species - metabolism Receptor, Adenosine A2A - genetics RNA, Messenger - genetics Rodents Signal Transduction - genetics
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