A novel pathway for the synthesis of inositol phospholipids uses cytidine diphosphate (CDP)-inositol as donor of the polar head group

Summary We describe a novel biosynthetic pathway for glycerophosphoinositides in Rhodothermus marinus in which inositol is activated by cytidine triphosphate (CTP); this is unlike all known pathways that involve activation of the lipid group instead. This work was motivated by the detection in the R...

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Veröffentlicht in:	Environmental microbiology 2015-07, Vol.17 (7), p.2492-2504
Hauptverfasser:	Jorge, Carla D., Borges, Nuno, Santos, Helena
Format:	Artikel
Sprache:	eng
Schlagworte:	Biosynthetic Pathways Cytidine Diphosphate - metabolism Cytidine Triphosphate - metabolism Enzymes Glycerol Inositol - metabolism Inositol Phosphates - metabolism Nucleotidyltransferases - metabolism Phosphatidylinositols - biosynthesis Rhodothermus - metabolism
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