Catalytic antibodies generated via heterologous immunization

The mechanism of a selected reaction constitutes a basis for the rational design of haptens which induce catalytic antibodies. Our recent studies on esterolytic antibodies suggested that efficient catalysis could be achieved with the aid of both acidic and basic amino acid residues appropriately dis...

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Veröffentlicht in:	Journal of the American Chemical Society 1994-06, Vol.116 (13), p.6025-6026
Hauptverfasser:	Suga, Hiroaki, Ersoy, Oguz, Williams, Simon F, Tsumuraya, Takeshi, Margolies, Michael N, Sinskey, Anthony J, Masamune, Satoru
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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