Erythropoietin increases hemoglobin during radiation therapy for cervical cancer

Purpose : Anemia during radiation therapy independently predicts poor outcome in patients with cervical cancer. Despite a randomized trial demonstrating red cell transfusions improve local control and survival, many patients are not transfused due to toxicity concerns. This study evaluates the effic...

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Veröffentlicht in:	International journal of radiation oncology, biology, physics biology, physics, 1994-07, Vol.29 (5), p.1079-1084
Hauptverfasser:	Dusenbery, Kathryn E., McGuire, Warren A., Holt, Penne J., Carson, Linda F., Fowler, Jeffrey M., Twiggs, Leo B., Potish, Roger A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anemia Anemia - blood Anemia - drug therapy Anemia - etiology Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Cervix cancer Erythropoietin (r-HuEPO) Erythropoietin - adverse effects Erythropoietin - blood Erythropoietin - therapeutic use Female Follow-Up Studies Hemoglobins - drug effects Hemoglobins - metabolism Hemoglobins - radiation effects Humans Medical sciences Middle Aged Pharmacology. Drug treatments Pilot Projects Quality of Life Radiation Injuries - blood Radiation Injuries - drug therapy Radiation Injuries - etiology Radiation therapy (RT) Recombinant Proteins - adverse effects Recombinant Proteins - blood Recombinant Proteins - therapeutic use Reticulocytes - radiation effects Uterine Cervical Neoplasms - blood Uterine Cervical Neoplasms - radiotherapy
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