Photodegradable Gelatin-Based Hydrogels Prepared by Bioorthogonal Click Chemistry for Cell Encapsulation and Release

In this study, we present a method for the fabrication of in situ forming gelatin and poly­(ethylene glycol)-based hydrogels utilizing bioorthogonal, strain-promoted alkyne–azide cycloaddition as the cross-linking reaction. By incorporating nitrobenzyl moieties within the network structure, these hy...

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Veröffentlicht in:	Biomacromolecules 2015-07, Vol.16 (7), p.2246-2253
Hauptverfasser:	Truong, Vinh X, Tsang, Kelly M, Simon, George P, Boyd, Richard L, Evans, Richard A, Thissen, Helmut, Forsythe, John S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Culture Techniques - methods Cell Engineering Cells, Cultured Click Chemistry - methods Cycloaddition Reaction - methods Fibroblasts - cytology Gelatin - chemistry Hydrogels - chemical synthesis Hydrogels - chemistry Mice Photolysis
Online-Zugang:	Volltext
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