Individualistic approach to the management of complete hydatidiform mole with coexisting live fetus
Abstract Complete hydatidiform mole with a coexisting live fetus (CHMCF) is a rare obstetric occurrence. So far, approximately 177 cases have been documented in the literature with consequent 66 live births. We report a review article along with two cases of CHMCF, one presenting as incomplete abort...
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Veröffentlicht in: | European journal of obstetrics & gynecology and reproductive biology 2015-08, Vol.191, p.39-42 |
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container_title | European journal of obstetrics & gynecology and reproductive biology |
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creator | Rohilla, Minakshi Singh, Purnima Kaur, Jaswinder Jain, Vanita Gupta, Nalini Prasad, G.R.V |
description | Abstract Complete hydatidiform mole with a coexisting live fetus (CHMCF) is a rare obstetric occurrence. So far, approximately 177 cases have been documented in the literature with consequent 66 live births. We report a review article along with two cases of CHMCF, one presenting as incomplete abortion and other continued as CHMCF but terminated because of antepartum hemorrhage. Both had histopathologically proven one normal and other complete molar placenta with coexisting normal fetus. No evidence of persistent trophoblastic disease was observed. The dilemma of continuation versus termination of pregnancy is being emphasized in the review of literature. Pregnancy complicated by CHMCF may result in a viable live born infant in approximately one third of the cases. A potentially viable fetus with CHMCF may result in normal live birth with antecedent high risk maternal complications. A decision of termination of pregnancy in all CHMCF will however nullify all the chances of a live birth. An individualistic approach and an informed doctor patient consensus may improve the likely outcome. Appropriate counseling of the mother regarding high incidence of antenatal complications plays an integral part of decision of continuation of such pregnancies. |
doi_str_mv | 10.1016/j.ejogrb.2015.05.017 |
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So far, approximately 177 cases have been documented in the literature with consequent 66 live births. We report a review article along with two cases of CHMCF, one presenting as incomplete abortion and other continued as CHMCF but terminated because of antepartum hemorrhage. Both had histopathologically proven one normal and other complete molar placenta with coexisting normal fetus. No evidence of persistent trophoblastic disease was observed. The dilemma of continuation versus termination of pregnancy is being emphasized in the review of literature. Pregnancy complicated by CHMCF may result in a viable live born infant in approximately one third of the cases. A potentially viable fetus with CHMCF may result in normal live birth with antecedent high risk maternal complications. A decision of termination of pregnancy in all CHMCF will however nullify all the chances of a live birth. An individualistic approach and an informed doctor patient consensus may improve the likely outcome. Appropriate counseling of the mother regarding high incidence of antenatal complications plays an integral part of decision of continuation of such pregnancies.</description><identifier>ISSN: 0301-2115</identifier><identifier>EISSN: 1872-7654</identifier><identifier>DOI: 10.1016/j.ejogrb.2015.05.017</identifier><identifier>PMID: 26070126</identifier><language>eng</language><publisher>Ireland: Elsevier Ireland Ltd</publisher><subject>Abortion, Incomplete - diagnosis ; Abortion, Induced ; Co-existent live fetus ; Complete mole ; Diagnosis, Differential ; Female ; Humans ; Hydatidiform Mole - diagnosis ; Hydatidiform Mole - therapy ; Live Birth ; Obstetrics and Gynecology ; Precision Medicine ; Pregnancy ; Pregnancy Complications, Neoplastic - diagnosis ; Pregnancy Complications, Neoplastic - therapy ; Pregnancy, Twin ; Twin pregnancy ; Uterine Neoplasms - diagnosis ; Uterine Neoplasms - therapy</subject><ispartof>European journal of obstetrics & gynecology and reproductive biology, 2015-08, Vol.191, p.39-42</ispartof><rights>Elsevier Ireland Ltd</rights><rights>2015 Elsevier Ireland Ltd</rights><rights>Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c417t-bce6758a3ca1d3390514625705934bbf4bbabf19bb1c3410f273b728eec0a8da3</citedby><cites>FETCH-LOGICAL-c417t-bce6758a3ca1d3390514625705934bbf4bbabf19bb1c3410f273b728eec0a8da3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0301211515001700$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26070126$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rohilla, Minakshi</creatorcontrib><creatorcontrib>Singh, Purnima</creatorcontrib><creatorcontrib>Kaur, Jaswinder</creatorcontrib><creatorcontrib>Jain, Vanita</creatorcontrib><creatorcontrib>Gupta, Nalini</creatorcontrib><creatorcontrib>Prasad, G.R.V</creatorcontrib><title>Individualistic approach to the management of complete hydatidiform mole with coexisting live fetus</title><title>European journal of obstetrics & gynecology and reproductive biology</title><addtitle>Eur J Obstet Gynecol Reprod Biol</addtitle><description>Abstract Complete hydatidiform mole with a coexisting live fetus (CHMCF) is a rare obstetric occurrence. So far, approximately 177 cases have been documented in the literature with consequent 66 live births. We report a review article along with two cases of CHMCF, one presenting as incomplete abortion and other continued as CHMCF but terminated because of antepartum hemorrhage. Both had histopathologically proven one normal and other complete molar placenta with coexisting normal fetus. No evidence of persistent trophoblastic disease was observed. The dilemma of continuation versus termination of pregnancy is being emphasized in the review of literature. Pregnancy complicated by CHMCF may result in a viable live born infant in approximately one third of the cases. A potentially viable fetus with CHMCF may result in normal live birth with antecedent high risk maternal complications. A decision of termination of pregnancy in all CHMCF will however nullify all the chances of a live birth. An individualistic approach and an informed doctor patient consensus may improve the likely outcome. Appropriate counseling of the mother regarding high incidence of antenatal complications plays an integral part of decision of continuation of such pregnancies.</description><subject>Abortion, Incomplete - diagnosis</subject><subject>Abortion, Induced</subject><subject>Co-existent live fetus</subject><subject>Complete mole</subject><subject>Diagnosis, Differential</subject><subject>Female</subject><subject>Humans</subject><subject>Hydatidiform Mole - diagnosis</subject><subject>Hydatidiform Mole - therapy</subject><subject>Live Birth</subject><subject>Obstetrics and Gynecology</subject><subject>Precision Medicine</subject><subject>Pregnancy</subject><subject>Pregnancy Complications, Neoplastic - diagnosis</subject><subject>Pregnancy Complications, Neoplastic - therapy</subject><subject>Pregnancy, Twin</subject><subject>Twin pregnancy</subject><subject>Uterine Neoplasms - diagnosis</subject><subject>Uterine Neoplasms - therapy</subject><issn>0301-2115</issn><issn>1872-7654</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFUcuO1DAQtBCIHRb-ACEfuWRwOw9PLkhoxWOllTgAZ8uPzoyDEw-2M8v8PY5mlwMXrLb64KpqdxUhr4FtgUH3btziGPZRbzmDdstKgXhCNrATvBJd2zwlG1YzqDhAe0VepDSycuq6f06ueMcEA95tiLmdrTs5uyjvUnaGquMxBmUONAeaD0gnNas9TjhnGgZqwnT0mJEezlZlZ90Q4kSn4JHeu3wo7_h71Zn31LsT0gHzkl6SZ4PyCV899Gvy49PH7zdfqruvn29vPtxVpgGRK22wE-1O1UaBLf9kLTQdbwVr-7rReihX6QF6rcHUDbCBi1oLvkM0TO2sqq_J24tu2eDXginLySWD3qsZw5IkdH0Hfds1vECbC9TEkFLEQR6jm1Q8S2BytVeO8mKvXO2VrBSIQnvzMGHRE9q_pEc_C-D9BYBlz5PDKJNxOBu0LqLJ0gb3vwn_ChjvZmeU_4lnTGNY4lw8lCATl0x-WyNeE4aWFXrJ9w-lkqPY</recordid><startdate>20150801</startdate><enddate>20150801</enddate><creator>Rohilla, Minakshi</creator><creator>Singh, Purnima</creator><creator>Kaur, Jaswinder</creator><creator>Jain, Vanita</creator><creator>Gupta, Nalini</creator><creator>Prasad, G.R.V</creator><general>Elsevier Ireland Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20150801</creationdate><title>Individualistic approach to the management of complete hydatidiform mole with coexisting live fetus</title><author>Rohilla, Minakshi ; Singh, Purnima ; Kaur, Jaswinder ; Jain, Vanita ; Gupta, Nalini ; Prasad, G.R.V</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c417t-bce6758a3ca1d3390514625705934bbf4bbabf19bb1c3410f273b728eec0a8da3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Abortion, Incomplete - diagnosis</topic><topic>Abortion, Induced</topic><topic>Co-existent live fetus</topic><topic>Complete mole</topic><topic>Diagnosis, Differential</topic><topic>Female</topic><topic>Humans</topic><topic>Hydatidiform Mole - diagnosis</topic><topic>Hydatidiform Mole - therapy</topic><topic>Live Birth</topic><topic>Obstetrics and Gynecology</topic><topic>Precision Medicine</topic><topic>Pregnancy</topic><topic>Pregnancy Complications, Neoplastic - diagnosis</topic><topic>Pregnancy Complications, Neoplastic - therapy</topic><topic>Pregnancy, Twin</topic><topic>Twin pregnancy</topic><topic>Uterine Neoplasms - diagnosis</topic><topic>Uterine Neoplasms - therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rohilla, Minakshi</creatorcontrib><creatorcontrib>Singh, Purnima</creatorcontrib><creatorcontrib>Kaur, Jaswinder</creatorcontrib><creatorcontrib>Jain, Vanita</creatorcontrib><creatorcontrib>Gupta, Nalini</creatorcontrib><creatorcontrib>Prasad, G.R.V</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of obstetrics & gynecology and reproductive biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rohilla, Minakshi</au><au>Singh, Purnima</au><au>Kaur, Jaswinder</au><au>Jain, Vanita</au><au>Gupta, Nalini</au><au>Prasad, G.R.V</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Individualistic approach to the management of complete hydatidiform mole with coexisting live fetus</atitle><jtitle>European journal of obstetrics & gynecology and reproductive biology</jtitle><addtitle>Eur J Obstet Gynecol Reprod Biol</addtitle><date>2015-08-01</date><risdate>2015</risdate><volume>191</volume><spage>39</spage><epage>42</epage><pages>39-42</pages><issn>0301-2115</issn><eissn>1872-7654</eissn><abstract>Abstract Complete hydatidiform mole with a coexisting live fetus (CHMCF) is a rare obstetric occurrence. So far, approximately 177 cases have been documented in the literature with consequent 66 live births. We report a review article along with two cases of CHMCF, one presenting as incomplete abortion and other continued as CHMCF but terminated because of antepartum hemorrhage. Both had histopathologically proven one normal and other complete molar placenta with coexisting normal fetus. No evidence of persistent trophoblastic disease was observed. The dilemma of continuation versus termination of pregnancy is being emphasized in the review of literature. Pregnancy complicated by CHMCF may result in a viable live born infant in approximately one third of the cases. A potentially viable fetus with CHMCF may result in normal live birth with antecedent high risk maternal complications. A decision of termination of pregnancy in all CHMCF will however nullify all the chances of a live birth. An individualistic approach and an informed doctor patient consensus may improve the likely outcome. Appropriate counseling of the mother regarding high incidence of antenatal complications plays an integral part of decision of continuation of such pregnancies.</abstract><cop>Ireland</cop><pub>Elsevier Ireland Ltd</pub><pmid>26070126</pmid><doi>10.1016/j.ejogrb.2015.05.017</doi><tpages>4</tpages></addata></record> |
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subjects | Abortion, Incomplete - diagnosis Abortion, Induced Co-existent live fetus Complete mole Diagnosis, Differential Female Humans Hydatidiform Mole - diagnosis Hydatidiform Mole - therapy Live Birth Obstetrics and Gynecology Precision Medicine Pregnancy Pregnancy Complications, Neoplastic - diagnosis Pregnancy Complications, Neoplastic - therapy Pregnancy, Twin Twin pregnancy Uterine Neoplasms - diagnosis Uterine Neoplasms - therapy |
title | Individualistic approach to the management of complete hydatidiform mole with coexisting live fetus |
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