Bispecific antibodies

Bispecific antibodies (bsAbs) combine specificities of two antibodies and simultaneously address different antigens or epitopes. BsAbs with ‘two-target’ functionality can interfere with multiple surface receptors or ligands associated, for example with cancer, proliferation or inflammatory processes...

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Bibliographische Detailangaben
Veröffentlicht in:	Drug discovery today 2015-07, Vol.20 (7), p.838-847
Hauptverfasser:	Kontermann, Roland E., Brinkmann, Ulrich
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - immunology Anti-Inflammatory Agents - therapeutic use Antibodies, Bispecific - immunology Antibodies, Bispecific - therapeutic use Antibody Specificity Antineoplastic Agents - immunology Antineoplastic Agents - therapeutic use Binding Sites, Antibody Epitopes, T-Lymphocyte Humans Immunotherapy - methods Recombinant Proteins - therapeutic use Signal Transduction - drug effects T-Lymphocytes - drug effects T-Lymphocytes - immunology T-Lymphocytes - metabolism
Online-Zugang:	Volltext
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