Systemic inflammation and oxidative stress in hemodialysis patients are associated with down-regulation of Nrf2

Background Oxidative stress and inflammation are common features and the main mediators of progression of chronic kidney disease (CKD) and its cardiovascular complications. Under normal conditions, oxidative stress activates the transcription factor, nuclear factor E2-related factor 2 (Nrf2), which...

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Veröffentlicht in:	Journal of nephrology 2015-08, Vol.28 (4), p.495-501
Hauptverfasser:	Pedruzzi, Liliana M., Cardozo, Ludmila F. M. F., Daleprane, Julio B., Stockler-Pinto, Milena B., Monteiro, Elisa B., Leite, Maurilo, Vaziri, Nosratola D., Mafra, Denise
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biomarkers - blood Case-Control Studies Down-Regulation Female Humans Inflammation - blood Inflammation - diagnosis Inflammation - etiology Inflammation - genetics Inflammation - immunology Inflammation Mediators - blood Leukocytes, Mononuclear - immunology Leukocytes, Mononuclear - metabolism Male Malondialdehyde - blood Medicine Medicine & Public Health Middle Aged NAD(P)H Dehydrogenase (Quinone) - genetics NAD(P)H Dehydrogenase (Quinone) - metabolism Nephrology NF-E2-Related Factor 2 - genetics NF-E2-Related Factor 2 - metabolism NF-kappa B - metabolism Original Article Oxidative Stress Renal Dialysis - adverse effects Renal Insufficiency, Chronic - blood Renal Insufficiency, Chronic - diagnosis Renal Insufficiency, Chronic - immunology Renal Insufficiency, Chronic - therapy RNA, Messenger - metabolism Tumor Necrosis Factor-alpha - blood Urology
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