Novel central action of des-Asp-angiotensin I

Intracerebroventricularly administered des-Asp-angiotensin I, when prevented from degradation by prior administration of captopril, attenuated dose-dependently the central pressor actions of angiotensin II and angiotensin III in the spontaneously hypertensive (SHR) and Wistar Kyoto (WKY) rats. This...

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Veröffentlicht in:	European journal of pharmacology 1994-05, Vol.257 (1), p.R1-R3
Hauptverfasser:	Sim, M.K., Radhakrishnan, R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin I - analogs & derivatives Angiotensin I - pharmacology Angiotensin II - antagonists & inhibitors Angiotensin III Angiotensin III - antagonists & inhibitors Animals Biological and medical sciences Blood Pressure - drug effects Captopril - pharmacology des-Asp-Angiotensin I Dose-Response Relationship, Drug Drug Interactions Endocrine kidney. Renin-angiotensin-aldosterone system Fundamental and applied biological sciences. Psychology Hypothalamus - drug effects Injections, Intraventricular Male Rats Rats, Inbred SHR Rats, Inbred WKY Spontaneously hypertensive rat (SHR) Vertebrates: endocrinology
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