Characteristics of episodic breathlessness as reported by patients with advanced chronic obstructive pulmonary disease and lung cancer: Results of a descriptive cohort study

Background: Episodic breathlessness is one form of refractory breathlessness. Better understanding of the symptom is necessary for effective management. Aim: The aim was to describe the characteristics of episodic breathlessness in patients with advanced chronic obstructive pulmonary disease or lung...

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Veröffentlicht in:Palliative medicine 2015-05, Vol.29 (5), p.420-428
Hauptverfasser: Weingärtner, Vera, Scheve, Christine, Gerdes, Verena, Schwarz-Eywill, Michael, Prenzel, Regina, Otremba, Burkhard, Mühlenbrock, Juliane, Bausewein, Claudia, Higginson, Irene J, Voltz, Raymond, Herich, Lena, Simon, Steffen T
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container_issue 5
container_start_page 420
container_title Palliative medicine
container_volume 29
creator Weingärtner, Vera
Scheve, Christine
Gerdes, Verena
Schwarz-Eywill, Michael
Prenzel, Regina
Otremba, Burkhard
Mühlenbrock, Juliane
Bausewein, Claudia
Higginson, Irene J
Voltz, Raymond
Herich, Lena
Simon, Steffen T
description Background: Episodic breathlessness is one form of refractory breathlessness. Better understanding of the symptom is necessary for effective management. Aim: The aim was to describe the characteristics of episodic breathlessness in patients with advanced chronic obstructive pulmonary disease or lung cancer. Design: This is a longitudinal cohort study. Outcomes were assessed monthly by up to 13 telephone interviews: peak severity (modified Borg scale: 0–10), duration, frequency, and timing of breathlessness episodes. Data from each episode were pooled and analyzed using descriptive statistics. Associations between outcomes were explored by correlation coefficients. Setting/participants: Patients with chronic obstructive pulmonary disease (Global Initiative for Chronic Obstructive Lung Disease classification stage III or IV) or primary lung cancer (any stage) were recruited in two inpatient units (internal medicine) and two outpatient clinics in Oldenburg, Germany. Results: A total of 82 patients (50 chronic obstructive pulmonary disease, 32 lung cancer), mean age (standard deviation) 67 years (8 years) and 36% female, were included reporting on 592 breathlessness episodes (chronic obstructive pulmonary disease: 403, lung cancer: 189). Peak severity was perceived significantly higher in chronic obstructive pulmonary disease patients than in lung cancer patients (mean (standard deviation) Borg scale: 6.2 (2.1) vs 4.2 (1.9); p 
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Better understanding of the symptom is necessary for effective management. Aim: The aim was to describe the characteristics of episodic breathlessness in patients with advanced chronic obstructive pulmonary disease or lung cancer. Design: This is a longitudinal cohort study. Outcomes were assessed monthly by up to 13 telephone interviews: peak severity (modified Borg scale: 0–10), duration, frequency, and timing of breathlessness episodes. Data from each episode were pooled and analyzed using descriptive statistics. Associations between outcomes were explored by correlation coefficients. Setting/participants: Patients with chronic obstructive pulmonary disease (Global Initiative for Chronic Obstructive Lung Disease classification stage III or IV) or primary lung cancer (any stage) were recruited in two inpatient units (internal medicine) and two outpatient clinics in Oldenburg, Germany. Results: A total of 82 patients (50 chronic obstructive pulmonary disease, 32 lung cancer), mean age (standard deviation) 67 years (8 years) and 36% female, were included reporting on 592 breathlessness episodes (chronic obstructive pulmonary disease: 403, lung cancer: 189). Peak severity was perceived significantly higher in chronic obstructive pulmonary disease patients than in lung cancer patients (mean (standard deviation) Borg scale: 6.2 (2.1) vs 4.2 (1.9); p &lt; 0.001). Episodes described by chronic obstructive pulmonary disease patients were longer than those described by lung cancer patients (median (range): 7 min (0–600) vs 5 min (0.3–120), p = 0.002)). Frequency was similar and most often daily in both groups. Severity and frequency of episodes were correlated in lung cancer patients (r = 0.324, p = 0.009). Conclusion: Most breathlessness episodes are short (minutes) and severe with significant differences between chronic obstructive pulmonary disease and lung cancer patients. Effective management strategies are warranted to improve symptom relief and coping.</description><identifier>ISSN: 0269-2163</identifier><identifier>EISSN: 1477-030X</identifier><identifier>DOI: 10.1177/0269216314563428</identifier><identifier>PMID: 25634633</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Chronic illnesses ; Chronic obstructive pulmonary disease ; Cohort analysis ; Dyspnea ; Dyspnea - epidemiology ; Dyspnea - etiology ; Dyspnea - physiopathology ; Epidemiology ; Female ; Germany - epidemiology ; Hospitals ; Humans ; Internal medicine ; Longitudinal Studies ; Lung cancer ; Lung diseases ; Lung Neoplasms - complications ; Male ; Medicine ; Middle Aged ; Palliative care ; Prospective Studies ; Pulmonary Disease, Chronic Obstructive - complications ; Severity of Illness Index</subject><ispartof>Palliative medicine, 2015-05, Vol.29 (5), p.420-428</ispartof><rights>The Author(s) 2015</rights><rights>The Author(s) 2015.</rights><rights>SAGE Publications © May 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c440t-f6ddd56dd22b8678890901a22c4b5b3e1399c361431e37bd892a24a43ab480763</citedby><cites>FETCH-LOGICAL-c440t-f6ddd56dd22b8678890901a22c4b5b3e1399c361431e37bd892a24a43ab480763</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/0269216314563428$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/0269216314563428$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,776,780,12825,21798,27901,27902,30976,43597,43598</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25634633$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Weingärtner, Vera</creatorcontrib><creatorcontrib>Scheve, Christine</creatorcontrib><creatorcontrib>Gerdes, Verena</creatorcontrib><creatorcontrib>Schwarz-Eywill, Michael</creatorcontrib><creatorcontrib>Prenzel, Regina</creatorcontrib><creatorcontrib>Otremba, Burkhard</creatorcontrib><creatorcontrib>Mühlenbrock, Juliane</creatorcontrib><creatorcontrib>Bausewein, Claudia</creatorcontrib><creatorcontrib>Higginson, Irene J</creatorcontrib><creatorcontrib>Voltz, Raymond</creatorcontrib><creatorcontrib>Herich, Lena</creatorcontrib><creatorcontrib>Simon, Steffen T</creatorcontrib><creatorcontrib>PAALiativ</creatorcontrib><title>Characteristics of episodic breathlessness as reported by patients with advanced chronic obstructive pulmonary disease and lung cancer: Results of a descriptive cohort study</title><title>Palliative medicine</title><addtitle>Palliat Med</addtitle><description>Background: Episodic breathlessness is one form of refractory breathlessness. Better understanding of the symptom is necessary for effective management. Aim: The aim was to describe the characteristics of episodic breathlessness in patients with advanced chronic obstructive pulmonary disease or lung cancer. Design: This is a longitudinal cohort study. Outcomes were assessed monthly by up to 13 telephone interviews: peak severity (modified Borg scale: 0–10), duration, frequency, and timing of breathlessness episodes. Data from each episode were pooled and analyzed using descriptive statistics. Associations between outcomes were explored by correlation coefficients. Setting/participants: Patients with chronic obstructive pulmonary disease (Global Initiative for Chronic Obstructive Lung Disease classification stage III or IV) or primary lung cancer (any stage) were recruited in two inpatient units (internal medicine) and two outpatient clinics in Oldenburg, Germany. Results: A total of 82 patients (50 chronic obstructive pulmonary disease, 32 lung cancer), mean age (standard deviation) 67 years (8 years) and 36% female, were included reporting on 592 breathlessness episodes (chronic obstructive pulmonary disease: 403, lung cancer: 189). Peak severity was perceived significantly higher in chronic obstructive pulmonary disease patients than in lung cancer patients (mean (standard deviation) Borg scale: 6.2 (2.1) vs 4.2 (1.9); p &lt; 0.001). Episodes described by chronic obstructive pulmonary disease patients were longer than those described by lung cancer patients (median (range): 7 min (0–600) vs 5 min (0.3–120), p = 0.002)). Frequency was similar and most often daily in both groups. Severity and frequency of episodes were correlated in lung cancer patients (r = 0.324, p = 0.009). 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Effective management strategies are warranted to improve symptom relief and coping.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Chronic illnesses</subject><subject>Chronic obstructive pulmonary disease</subject><subject>Cohort analysis</subject><subject>Dyspnea</subject><subject>Dyspnea - epidemiology</subject><subject>Dyspnea - etiology</subject><subject>Dyspnea - physiopathology</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Germany - epidemiology</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Internal medicine</subject><subject>Longitudinal Studies</subject><subject>Lung cancer</subject><subject>Lung diseases</subject><subject>Lung Neoplasms - complications</subject><subject>Male</subject><subject>Medicine</subject><subject>Middle Aged</subject><subject>Palliative care</subject><subject>Prospective Studies</subject><subject>Pulmonary Disease, Chronic Obstructive - complications</subject><subject>Severity of Illness Index</subject><issn>0269-2163</issn><issn>1477-030X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><sourceid>BENPR</sourceid><recordid>eNqNkU-L1TAUxYMozpvRvSsJuHFTzb-mjTt56CgMCKLgrqTJfdMMfU3NTUfeh_I7mr43igwILpIs7u-cw80h5BlnrzhvmtdMaCO4llzVWirRPiAbrpqmYpJ9e0g267ha52fkHPGGMS6ZVo_JmVhxLeWG_NwONlmXIQXMwSGNOwpzwOiDo30Cm4cREKdyqEWaYI4pg6f9gc42B5gy0h8hD9T6Wzu5MnFDilMRxx5zWlwOt0DnZdzHyaYD9QHBIlA7eTou0zV1qyq9oZ8BlzEf8y31gC6F-ah1cSiRFPPiD0_Io50dEZ7evRfk6_t3X7YfqqtPlx-3b68qpxTL1U577-tyCdG3umlbwwzjVgin-rqXwKUxTmquJAfZ9L41wgpllbS9almj5QV5efKdU_y-AOZuH9DBONoJ4oId16YWzLSq_g-0UaY2jVpdX9xDb-KSprLIkVKlKWMKxU6USxExwa6bU9iXv-s469bWu_utF8nzO-Ol34P_I_hdcwGqE4D2Gv5K_ZfhL1C8tww</recordid><startdate>20150501</startdate><enddate>20150501</enddate><creator>Weingärtner, Vera</creator><creator>Scheve, Christine</creator><creator>Gerdes, Verena</creator><creator>Schwarz-Eywill, Michael</creator><creator>Prenzel, Regina</creator><creator>Otremba, Burkhard</creator><creator>Mühlenbrock, Juliane</creator><creator>Bausewein, Claudia</creator><creator>Higginson, Irene J</creator><creator>Voltz, Raymond</creator><creator>Herich, Lena</creator><creator>Simon, Steffen T</creator><general>SAGE Publications</general><general>Sage Publications Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7QJ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AN0</scope><scope>ASE</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FPQ</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HEHIP</scope><scope>K6X</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2S</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20150501</creationdate><title>Characteristics of episodic breathlessness as reported by patients with advanced chronic obstructive pulmonary disease and lung cancer: Results of a descriptive cohort study</title><author>Weingärtner, Vera ; 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Better understanding of the symptom is necessary for effective management. Aim: The aim was to describe the characteristics of episodic breathlessness in patients with advanced chronic obstructive pulmonary disease or lung cancer. Design: This is a longitudinal cohort study. Outcomes were assessed monthly by up to 13 telephone interviews: peak severity (modified Borg scale: 0–10), duration, frequency, and timing of breathlessness episodes. Data from each episode were pooled and analyzed using descriptive statistics. Associations between outcomes were explored by correlation coefficients. Setting/participants: Patients with chronic obstructive pulmonary disease (Global Initiative for Chronic Obstructive Lung Disease classification stage III or IV) or primary lung cancer (any stage) were recruited in two inpatient units (internal medicine) and two outpatient clinics in Oldenburg, Germany. Results: A total of 82 patients (50 chronic obstructive pulmonary disease, 32 lung cancer), mean age (standard deviation) 67 years (8 years) and 36% female, were included reporting on 592 breathlessness episodes (chronic obstructive pulmonary disease: 403, lung cancer: 189). Peak severity was perceived significantly higher in chronic obstructive pulmonary disease patients than in lung cancer patients (mean (standard deviation) Borg scale: 6.2 (2.1) vs 4.2 (1.9); p &lt; 0.001). Episodes described by chronic obstructive pulmonary disease patients were longer than those described by lung cancer patients (median (range): 7 min (0–600) vs 5 min (0.3–120), p = 0.002)). Frequency was similar and most often daily in both groups. Severity and frequency of episodes were correlated in lung cancer patients (r = 0.324, p = 0.009). Conclusion: Most breathlessness episodes are short (minutes) and severe with significant differences between chronic obstructive pulmonary disease and lung cancer patients. Effective management strategies are warranted to improve symptom relief and coping.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>25634633</pmid><doi>10.1177/0269216314563428</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record>
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source Applied Social Sciences Index & Abstracts (ASSIA); MEDLINE; SAGE Complete
subjects Adult
Aged
Aged, 80 and over
Chronic illnesses
Chronic obstructive pulmonary disease
Cohort analysis
Dyspnea
Dyspnea - epidemiology
Dyspnea - etiology
Dyspnea - physiopathology
Epidemiology
Female
Germany - epidemiology
Hospitals
Humans
Internal medicine
Longitudinal Studies
Lung cancer
Lung diseases
Lung Neoplasms - complications
Male
Medicine
Middle Aged
Palliative care
Prospective Studies
Pulmonary Disease, Chronic Obstructive - complications
Severity of Illness Index
title Characteristics of episodic breathlessness as reported by patients with advanced chronic obstructive pulmonary disease and lung cancer: Results of a descriptive cohort study
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