RNA Binding Protein Nanos2 Organizes Post-transcriptional Buffering System to Retain Primitive State of Mouse Spermatogonial Stem Cells

In many adult tissues, homeostasis relies on self-renewing stem cells that are primed for differentiation. The reconciliation mechanisms of these characteristics remain a fundamental question in stem cell biology. We propose that regulation at the post-transcriptional level is essential for homeosta...

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Veröffentlicht in:	Developmental cell 2015-07, Vol.34 (1), p.96-107
Hauptverfasser:	Zhou, Zhi, Shirakawa, Takayuki, Ohbo, Kazuyuki, Sada, Aiko, Wu, Quan, Hasegawa, Kazuteru, Saba, Rie, Saga, Yumiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Differentiation - physiology Cell Proliferation - physiology Gene Expression Regulation - physiology Male Mice RNA - metabolism RNA-Binding Proteins - genetics Signal Transduction - physiology Spermatogonia - cytology Stem Cells - cytology
Online-Zugang:	Volltext
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