Genetic polymorphism of 13 non-CODIS STR loci in three national populations from China
The aim of this study was to investigate a 13 non‐CODIS STR loci database using three national populations from China. A new multiplex PCR system that simultaneously amplified 13 loci in the same PCR reaction was developed. This multiplex system included the 13 STR markers (D3S2402, D3S2452, D3S1766...
Gespeichert in:
| Veröffentlicht in: | Electrophoresis 2014-12, Vol.35 (23), p.3395-3401 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 3401 |
|---|---|
| container_issue | 23 |
| container_start_page | 3395 |
| container_title | Electrophoresis |
| container_volume | 35 |
| creator | Liu, Qiu-Ling Huang, Kai-Kai Wu, Ye-Da Zhao, Hu Li, Cheng-tao Lu, De-Jian |
| description | The aim of this study was to investigate a 13 non‐CODIS STR loci database using three national populations from China. A new multiplex PCR system that simultaneously amplified 13 loci in the same PCR reaction was developed. This multiplex system included the 13 STR markers (D3S2402, D3S2452, D3S1766, D3S4554, D3S2388, D3S3051, D3S3053, D4S2364, D4S2404, AC001348A, AC001348B, D17S975, and D17S1294), which were successfully analyzed by using 441 DNA samples from three national populations in China (154 Mongol, 177 Kazakh, and 110 Uigur). Allele frequencies and mutation rates of the 13 non‐CODIS STR loci were investigated. A total of 4–10 alleles at each locus were observed and altogether 84, 88, and 87 alleles for the all selected loci were found in the Mongol, Kazakh, and Uigur, respectively. Eight mutations were detected from the 13 selected loci in 9880 meioses in kinship cases. These results indicate that this multiplex system may provide significant polymorphic information for kinship testing and relationship investigations. |
| doi_str_mv | 10.1002/elps.201400290 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1694985544</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1694985544</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4445-117861f10120ec58b3d949dad4b39c420bcbd6a37e68e458705669e72d8f29873</originalsourceid><addsrcrecordid>eNqNkc1P2zAYh60JNDq2K0fkI5cUf38cpwIFqYKJAjtaTuKoBifO7FRb_3vSFXqF06tXep7n8gPgBKMpRoicu9DnKUGYjY9GX8AEc0IKIhQ9ABOEJS2QovwIfMv5GSHENGNfwRHhoywEn4Cnuevc4CvYx7BpY-pXPrcwNhBT2MWumN1d3Czh8uEehlh56Ds4rJJzsLODj50No9evw_8nwybFFs5WvrPfwWFjQ3Y_3u4xeLy6fJhdF4u7-c3s56KoGGO8wFgqgRuMMEGu4qqktWa6tjUrqa4YQWVV1sJS6YRyjCuJuBDaSVKrhmgl6TE423X7FP-sXR5M63PlQrCdi-tssBh7inPGPoFyzDBX6DMo0VpIosWITndolWLOyTWmT761aWMwMtuFzHYhs19oFE7f2uuydfUef59kBNgO-OuD23yQM5eLX0tO2FYrdprPg_u312x6MUJSyc3v27m5J-SKEnVhbukrejuoHQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1629967296</pqid></control><display><type>article</type><title>Genetic polymorphism of 13 non-CODIS STR loci in three national populations from China</title><source>MEDLINE</source><source>Access via Wiley Online Library</source><creator>Liu, Qiu-Ling ; Huang, Kai-Kai ; Wu, Ye-Da ; Zhao, Hu ; Li, Cheng-tao ; Lu, De-Jian</creator><creatorcontrib>Liu, Qiu-Ling ; Huang, Kai-Kai ; Wu, Ye-Da ; Zhao, Hu ; Li, Cheng-tao ; Lu, De-Jian</creatorcontrib><description>The aim of this study was to investigate a 13 non‐CODIS STR loci database using three national populations from China. A new multiplex PCR system that simultaneously amplified 13 loci in the same PCR reaction was developed. This multiplex system included the 13 STR markers (D3S2402, D3S2452, D3S1766, D3S4554, D3S2388, D3S3051, D3S3053, D4S2364, D4S2404, AC001348A, AC001348B, D17S975, and D17S1294), which were successfully analyzed by using 441 DNA samples from three national populations in China (154 Mongol, 177 Kazakh, and 110 Uigur). Allele frequencies and mutation rates of the 13 non‐CODIS STR loci were investigated. A total of 4–10 alleles at each locus were observed and altogether 84, 88, and 87 alleles for the all selected loci were found in the Mongol, Kazakh, and Uigur, respectively. Eight mutations were detected from the 13 selected loci in 9880 meioses in kinship cases. These results indicate that this multiplex system may provide significant polymorphic information for kinship testing and relationship investigations.</description><identifier>ISSN: 0173-0835</identifier><identifier>EISSN: 1522-2683</identifier><identifier>DOI: 10.1002/elps.201400290</identifier><identifier>PMID: 25100665</identifier><language>eng</language><publisher>Germany: Blackwell Publishing Ltd</publisher><subject>Asian Continental Ancestry Group - genetics ; China ; Databases, Genetic ; Female ; Genetic Markers - genetics ; Genetic polymorphism ; Genetics ; Haplotype ; Humans ; Linkage ; Loci ; Male ; Markers ; Microsatellite Repeats ; Multiplex PCR ; Multiplex Polymerase Chain Reaction - methods ; Multiplexing ; Mutation - genetics ; Mutations ; Polymorphism, Genetic ; Populations ; STR</subject><ispartof>Electrophoresis, 2014-12, Vol.35 (23), p.3395-3401</ispartof><rights>2014 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim</rights><rights>2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4445-117861f10120ec58b3d949dad4b39c420bcbd6a37e68e458705669e72d8f29873</citedby><cites>FETCH-LOGICAL-c4445-117861f10120ec58b3d949dad4b39c420bcbd6a37e68e458705669e72d8f29873</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Felps.201400290$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Felps.201400290$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25100665$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Liu, Qiu-Ling</creatorcontrib><creatorcontrib>Huang, Kai-Kai</creatorcontrib><creatorcontrib>Wu, Ye-Da</creatorcontrib><creatorcontrib>Zhao, Hu</creatorcontrib><creatorcontrib>Li, Cheng-tao</creatorcontrib><creatorcontrib>Lu, De-Jian</creatorcontrib><title>Genetic polymorphism of 13 non-CODIS STR loci in three national populations from China</title><title>Electrophoresis</title><addtitle>ELECTROPHORESIS</addtitle><description>The aim of this study was to investigate a 13 non‐CODIS STR loci database using three national populations from China. A new multiplex PCR system that simultaneously amplified 13 loci in the same PCR reaction was developed. This multiplex system included the 13 STR markers (D3S2402, D3S2452, D3S1766, D3S4554, D3S2388, D3S3051, D3S3053, D4S2364, D4S2404, AC001348A, AC001348B, D17S975, and D17S1294), which were successfully analyzed by using 441 DNA samples from three national populations in China (154 Mongol, 177 Kazakh, and 110 Uigur). Allele frequencies and mutation rates of the 13 non‐CODIS STR loci were investigated. A total of 4–10 alleles at each locus were observed and altogether 84, 88, and 87 alleles for the all selected loci were found in the Mongol, Kazakh, and Uigur, respectively. Eight mutations were detected from the 13 selected loci in 9880 meioses in kinship cases. These results indicate that this multiplex system may provide significant polymorphic information for kinship testing and relationship investigations.</description><subject>Asian Continental Ancestry Group - genetics</subject><subject>China</subject><subject>Databases, Genetic</subject><subject>Female</subject><subject>Genetic Markers - genetics</subject><subject>Genetic polymorphism</subject><subject>Genetics</subject><subject>Haplotype</subject><subject>Humans</subject><subject>Linkage</subject><subject>Loci</subject><subject>Male</subject><subject>Markers</subject><subject>Microsatellite Repeats</subject><subject>Multiplex PCR</subject><subject>Multiplex Polymerase Chain Reaction - methods</subject><subject>Multiplexing</subject><subject>Mutation - genetics</subject><subject>Mutations</subject><subject>Polymorphism, Genetic</subject><subject>Populations</subject><subject>STR</subject><issn>0173-0835</issn><issn>1522-2683</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkc1P2zAYh60JNDq2K0fkI5cUf38cpwIFqYKJAjtaTuKoBifO7FRb_3vSFXqF06tXep7n8gPgBKMpRoicu9DnKUGYjY9GX8AEc0IKIhQ9ABOEJS2QovwIfMv5GSHENGNfwRHhoywEn4Cnuevc4CvYx7BpY-pXPrcwNhBT2MWumN1d3Czh8uEehlh56Ds4rJJzsLODj50No9evw_8nwybFFs5WvrPfwWFjQ3Y_3u4xeLy6fJhdF4u7-c3s56KoGGO8wFgqgRuMMEGu4qqktWa6tjUrqa4YQWVV1sJS6YRyjCuJuBDaSVKrhmgl6TE423X7FP-sXR5M63PlQrCdi-tssBh7inPGPoFyzDBX6DMo0VpIosWITndolWLOyTWmT761aWMwMtuFzHYhs19oFE7f2uuydfUef59kBNgO-OuD23yQM5eLX0tO2FYrdprPg_u312x6MUJSyc3v27m5J-SKEnVhbukrejuoHQ</recordid><startdate>201412</startdate><enddate>201412</enddate><creator>Liu, Qiu-Ling</creator><creator>Huang, Kai-Kai</creator><creator>Wu, Ye-Da</creator><creator>Zhao, Hu</creator><creator>Li, Cheng-tao</creator><creator>Lu, De-Jian</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7U5</scope><scope>8FD</scope><scope>L7M</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope></search><sort><creationdate>201412</creationdate><title>Genetic polymorphism of 13 non-CODIS STR loci in three national populations from China</title><author>Liu, Qiu-Ling ; Huang, Kai-Kai ; Wu, Ye-Da ; Zhao, Hu ; Li, Cheng-tao ; Lu, De-Jian</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4445-117861f10120ec58b3d949dad4b39c420bcbd6a37e68e458705669e72d8f29873</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Asian Continental Ancestry Group - genetics</topic><topic>China</topic><topic>Databases, Genetic</topic><topic>Female</topic><topic>Genetic Markers - genetics</topic><topic>Genetic polymorphism</topic><topic>Genetics</topic><topic>Haplotype</topic><topic>Humans</topic><topic>Linkage</topic><topic>Loci</topic><topic>Male</topic><topic>Markers</topic><topic>Microsatellite Repeats</topic><topic>Multiplex PCR</topic><topic>Multiplex Polymerase Chain Reaction - methods</topic><topic>Multiplexing</topic><topic>Mutation - genetics</topic><topic>Mutations</topic><topic>Polymorphism, Genetic</topic><topic>Populations</topic><topic>STR</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Liu, Qiu-Ling</creatorcontrib><creatorcontrib>Huang, Kai-Kai</creatorcontrib><creatorcontrib>Wu, Ye-Da</creatorcontrib><creatorcontrib>Zhao, Hu</creatorcontrib><creatorcontrib>Li, Cheng-tao</creatorcontrib><creatorcontrib>Lu, De-Jian</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><jtitle>Electrophoresis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Liu, Qiu-Ling</au><au>Huang, Kai-Kai</au><au>Wu, Ye-Da</au><au>Zhao, Hu</au><au>Li, Cheng-tao</au><au>Lu, De-Jian</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Genetic polymorphism of 13 non-CODIS STR loci in three national populations from China</atitle><jtitle>Electrophoresis</jtitle><addtitle>ELECTROPHORESIS</addtitle><date>2014-12</date><risdate>2014</risdate><volume>35</volume><issue>23</issue><spage>3395</spage><epage>3401</epage><pages>3395-3401</pages><issn>0173-0835</issn><eissn>1522-2683</eissn><abstract>The aim of this study was to investigate a 13 non‐CODIS STR loci database using three national populations from China. A new multiplex PCR system that simultaneously amplified 13 loci in the same PCR reaction was developed. This multiplex system included the 13 STR markers (D3S2402, D3S2452, D3S1766, D3S4554, D3S2388, D3S3051, D3S3053, D4S2364, D4S2404, AC001348A, AC001348B, D17S975, and D17S1294), which were successfully analyzed by using 441 DNA samples from three national populations in China (154 Mongol, 177 Kazakh, and 110 Uigur). Allele frequencies and mutation rates of the 13 non‐CODIS STR loci were investigated. A total of 4–10 alleles at each locus were observed and altogether 84, 88, and 87 alleles for the all selected loci were found in the Mongol, Kazakh, and Uigur, respectively. Eight mutations were detected from the 13 selected loci in 9880 meioses in kinship cases. These results indicate that this multiplex system may provide significant polymorphic information for kinship testing and relationship investigations.</abstract><cop>Germany</cop><pub>Blackwell Publishing Ltd</pub><pmid>25100665</pmid><doi>10.1002/elps.201400290</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0173-0835 |
| ispartof | Electrophoresis, 2014-12, Vol.35 (23), p.3395-3401 |
| issn | 0173-0835 1522-2683 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1694985544 |
| source | MEDLINE; Access via Wiley Online Library |
| subjects | Asian Continental Ancestry Group - genetics China Databases, Genetic Female Genetic Markers - genetics Genetic polymorphism Genetics Haplotype Humans Linkage Loci Male Markers Microsatellite Repeats Multiplex PCR Multiplex Polymerase Chain Reaction - methods Multiplexing Mutation - genetics Mutations Polymorphism, Genetic Populations STR |
| title | Genetic polymorphism of 13 non-CODIS STR loci in three national populations from China |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T16%3A10%3A15IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Genetic%20polymorphism%20of%2013%20non-CODIS%20STR%20loci%20in%20three%20national%20populations%20from%20China&rft.jtitle=Electrophoresis&rft.au=Liu,%20Qiu-Ling&rft.date=2014-12&rft.volume=35&rft.issue=23&rft.spage=3395&rft.epage=3401&rft.pages=3395-3401&rft.issn=0173-0835&rft.eissn=1522-2683&rft_id=info:doi/10.1002/elps.201400290&rft_dat=%3Cproquest_cross%3E1694985544%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1629967296&rft_id=info:pmid/25100665&rfr_iscdi=true |