SPS: A Simulation Tool for Calculating Power of Set-Based Genetic Association Tests

ABSTRACT Set‐based association tests, combining a set of single‐nucleotide polymorphisms into a unified test, have become important approaches to identify weak‐effect or low‐frequency risk loci of complex diseases. However, there is no comprehensive and user‐friendly tool to estimate power of set‐ba...

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Veröffentlicht in:	Genetic epidemiology 2015-07, Vol.39 (5), p.395-397
Hauptverfasser:	Li, Jiang, Sham, Pak Chung, Song, Youqiang, Li, Miaoxin
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Analysis of Variance complex disease Computer Simulation Genetic Association Studies - methods Genotype Humans meta-analysis Models, Genetic Monte Carlo Method Polymorphism Polymorphism, Single Nucleotide - genetics power set-based association test Simulation Software
Online-Zugang:	Volltext
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