Hepatitis B immunoprophylaxis failure and the presence of hepatitis B surface gene mutants in the affected children

Hepatitis B virus (HBV) infection is usually vertically transmitted from the mother to child during birth in Asian countries. Despite immunization, immunoprophylaxis failure is well‐documented. The aim of the study was to study immunoprophylaxis failure rate in the cohort of infants delivered by chr...

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Veröffentlicht in:	Journal of medical virology 2015-08, Vol.87 (8), p.1344-1350
Hauptverfasser:	Lee, Le Ye, Aw, Marion, Rauff, Mary, Loh, Kah-Sin, Lim, Seng Gee, Lee, Guan Huei
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Cohort Studies DNA, Viral - chemistry DNA, Viral - genetics Female Genetics Hepatitis Hepatitis B - prevention & control Hepatitis B - virology hepatitis B chronic carrier mothers Hepatitis B Surface Antigens - genetics hepatitis B surface gene mutations Hepatitis B virus Hepatitis B virus - genetics Hepatitis B virus - immunology Hepatitis B virus - isolation & purification Humans Immunization Immunization - methods immunoprophylaxis failure in children Infant Infant, Newborn Infectious Disease Transmission, Vertical - prevention & control Male maternal HBV DNA (viral load) Mutant Proteins - genetics Mutation Pediatrics Pregnancy Sequence Analysis, DNA Singapore Treatment Failure vertical transmission Virology Young Adult
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