Birth weight, infant mortality, and race: Twin comparisons and genetic/environmental inputs
Genetic and environmental inputs may shape population health disparities in varying ways. In this article, we use unique variation involved in twin births to attempt to untangle how genetic and prenatal environmental variation may make different contributions to infant health among white and black p...
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Veröffentlicht in: | Social science & medicine (1982) 2012-12, Vol.75 (12), p.2446-2454 |
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description | Genetic and environmental inputs may shape population health disparities in varying ways. In this article, we use unique variation involved in twin births to attempt to untangle how genetic and prenatal environmental variation may make different contributions to infant health among white and black populations in the United States. Using twin fixed effects models and data from the 1995–1997 Matched Multiple Birth Dataset we compare birth weight–mortality associations across twin sex composition, zygosity, and race. Findings reveal suggestive differences between fraternal and imputed identical twin estimates for white and black twin pairs.
► This study examines how genes and environment may shape race differences in birth weight and infant mortality. ► Twin estimates suggest that prenatal environment partially accounts for birth weight–mortality associations. ► Race differences in estimates highlight the need for further research into gene–environment interactions in health disparities. |
doi_str_mv | 10.1016/j.socscimed.2012.09.024 |
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► This study examines how genes and environment may shape race differences in birth weight and infant mortality. ► Twin estimates suggest that prenatal environment partially accounts for birth weight–mortality associations. ► Race differences in estimates highlight the need for further research into gene–environment interactions in health disparities.</description><identifier>ISSN: 0277-9536</identifier><identifier>EISSN: 1873-5347</identifier><identifier>DOI: 10.1016/j.socscimed.2012.09.024</identifier><identifier>PMID: 23083893</identifier><identifier>CODEN: SSMDEP</identifier><language>eng</language><publisher>Kidlington: Elsevier Ltd</publisher><subject>African Americans ; Biological and medical sciences ; Birth rate ; Birth weight ; Birth Weight - genetics ; Black White Relations ; Blacks ; Childrens health ; Databases, Factual ; Environment. Living conditions ; Epidemiology ; European Continental Ancestry Group ; Female ; General aspects ; Genetics ; Gene–environment interactions ; Health ; Health inequality ; Health Status Disparities ; Humans ; Inequality ; Infant ; Infant Mortality ; Infant, Newborn ; Infants ; Male ; Medical sciences ; Miscellaneous ; Population statistics ; Prenatal Care ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Race ; Racial Differences ; Social environment ; Twin Studies as Topic ; Twins ; U.S.A ; United States - epidemiology ; Whites</subject><ispartof>Social science & medicine (1982), 2012-12, Vol.75 (12), p.2446-2454</ispartof><rights>2012 Elsevier Ltd</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2012 Elsevier Ltd. All rights reserved.</rights><rights>Copyright Pergamon Press Inc. Dec 2012</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c594t-52ebade03063916c7e6242679854595420cdd7f24d341f89e19cd1e26db7c0dc3</citedby><cites>FETCH-LOGICAL-c594t-52ebade03063916c7e6242679854595420cdd7f24d341f89e19cd1e26db7c0dc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.socscimed.2012.09.024$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,33755,33756,45976</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26684939$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23083893$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Conley, Dalton</creatorcontrib><creatorcontrib>Strully, Kate W.</creatorcontrib><title>Birth weight, infant mortality, and race: Twin comparisons and genetic/environmental inputs</title><title>Social science & medicine (1982)</title><addtitle>Soc Sci Med</addtitle><description>Genetic and environmental inputs may shape population health disparities in varying ways. In this article, we use unique variation involved in twin births to attempt to untangle how genetic and prenatal environmental variation may make different contributions to infant health among white and black populations in the United States. Using twin fixed effects models and data from the 1995–1997 Matched Multiple Birth Dataset we compare birth weight–mortality associations across twin sex composition, zygosity, and race. Findings reveal suggestive differences between fraternal and imputed identical twin estimates for white and black twin pairs.
► This study examines how genes and environment may shape race differences in birth weight and infant mortality. ► Twin estimates suggest that prenatal environment partially accounts for birth weight–mortality associations. ► Race differences in estimates highlight the need for further research into gene–environment interactions in health disparities.</description><subject>African Americans</subject><subject>Biological and medical sciences</subject><subject>Birth rate</subject><subject>Birth weight</subject><subject>Birth Weight - genetics</subject><subject>Black White Relations</subject><subject>Blacks</subject><subject>Childrens health</subject><subject>Databases, Factual</subject><subject>Environment. Living conditions</subject><subject>Epidemiology</subject><subject>European Continental Ancestry Group</subject><subject>Female</subject><subject>General aspects</subject><subject>Genetics</subject><subject>Gene–environment interactions</subject><subject>Health</subject><subject>Health inequality</subject><subject>Health Status Disparities</subject><subject>Humans</subject><subject>Inequality</subject><subject>Infant</subject><subject>Infant Mortality</subject><subject>Infant, Newborn</subject><subject>Infants</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Miscellaneous</subject><subject>Population statistics</subject><subject>Prenatal Care</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Race</subject><subject>Racial Differences</subject><subject>Social environment</subject><subject>Twin Studies as Topic</subject><subject>Twins</subject><subject>U.S.A</subject><subject>United States - epidemiology</subject><subject>Whites</subject><issn>0277-9536</issn><issn>1873-5347</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BHHNA</sourceid><recordid>eNqNkk9v1DAQxSMEokvhK0AkhMShSf3fMbdS0YJUiUs5cbC89qT1KnEW22nVb4_DbkHisj3NYX7vzYz9quodRi1GWJxu2jTZZP0IriUIkxapFhH2rFrhTtKGUyafVytEpGwUp-KoepXSBiGEUUdfVkeEltopuqp-fvYx39b34G9u80ntQ29CrscpZjP4_HBSm-DqaCx8qq_vfajtNG5N9GkK6U_rBgJkb08h3Pk4hRFCERab7ZzT6-pFb4YEb_b1uPpx8eX6_Gtz9f3y2_nZVWO5YrnhBNbGAaJIUIWFlSAII0KqjjOuOCPIOid7whxluO8UYGUdBiLcWlrkLD2uPu58t3H6NUPKevTJwjCYANOcNBaKKUkwFU9Ay1xOpaRPQ5lUQh5GScfLTUqRwygupqqTeNn1_X_oZppjKC-5UJR0hHJcKLmjbJxSitDrbfSjiQ8aI71kRW_036zoJSsaKV2yUpRv9_7zeuk96h7DUYAPe8Aka4Y-mmB9-scJ0TFFVeHOdhyUT77zEHWZBsGC8xFs1m7yB5f5DVOf3og</recordid><startdate>20121201</startdate><enddate>20121201</enddate><creator>Conley, Dalton</creator><creator>Strully, Kate W.</creator><general>Elsevier Ltd</general><general>Elsevier</general><general>Pergamon Press Inc</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U3</scope><scope>7U4</scope><scope>8BJ</scope><scope>BHHNA</scope><scope>DWI</scope><scope>FQK</scope><scope>JBE</scope><scope>K9.</scope><scope>WZK</scope><scope>7X8</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope></search><sort><creationdate>20121201</creationdate><title>Birth weight, infant mortality, and race: Twin comparisons and genetic/environmental inputs</title><author>Conley, Dalton ; Strully, Kate W.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c594t-52ebade03063916c7e6242679854595420cdd7f24d341f89e19cd1e26db7c0dc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>African Americans</topic><topic>Biological and medical sciences</topic><topic>Birth rate</topic><topic>Birth weight</topic><topic>Birth Weight - genetics</topic><topic>Black White Relations</topic><topic>Blacks</topic><topic>Childrens health</topic><topic>Databases, Factual</topic><topic>Environment. 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In this article, we use unique variation involved in twin births to attempt to untangle how genetic and prenatal environmental variation may make different contributions to infant health among white and black populations in the United States. Using twin fixed effects models and data from the 1995–1997 Matched Multiple Birth Dataset we compare birth weight–mortality associations across twin sex composition, zygosity, and race. Findings reveal suggestive differences between fraternal and imputed identical twin estimates for white and black twin pairs.
► This study examines how genes and environment may shape race differences in birth weight and infant mortality. ► Twin estimates suggest that prenatal environment partially accounts for birth weight–mortality associations. ► Race differences in estimates highlight the need for further research into gene–environment interactions in health disparities.</abstract><cop>Kidlington</cop><pub>Elsevier Ltd</pub><pmid>23083893</pmid><doi>10.1016/j.socscimed.2012.09.024</doi><tpages>9</tpages></addata></record> |
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subjects | African Americans Biological and medical sciences Birth rate Birth weight Birth Weight - genetics Black White Relations Blacks Childrens health Databases, Factual Environment. Living conditions Epidemiology European Continental Ancestry Group Female General aspects Genetics Gene–environment interactions Health Health inequality Health Status Disparities Humans Inequality Infant Infant Mortality Infant, Newborn Infants Male Medical sciences Miscellaneous Population statistics Prenatal Care Public health. Hygiene Public health. Hygiene-occupational medicine Race Racial Differences Social environment Twin Studies as Topic Twins U.S.A United States - epidemiology Whites |
title | Birth weight, infant mortality, and race: Twin comparisons and genetic/environmental inputs |
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