Anti‐absence activity of mGlu1 and mGlu5 receptor enhancers and their interaction with a GABA reuptake inhibitor: Effect of local infusions in the somatosensory cortex and thalamus

Summary Objective Glutamate and γ‐aminobutyric acid (GABA) are the key neurotransmitter systems in the cortical‐thalamocortical network, involved in normal and pathologic oscillations such as spike‐wave discharges (SWDs), which characterize different forms of absence epilepsy. Metabotropic glutamate...

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