Downstream processing of polymer-based amorphous solid dispersions to generate tablet formulations

Application of amorphous solid dispersions (ASDs) is considered one of the most promising approaches to increase the dissolution rate and extent of bioavailability of poorly water soluble drugs. Such intervention is often required for new drug candidates in that enablement, bioavailability is not su...

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Veröffentlicht in:	International journal of pharmaceutics 2015-05, Vol.486 (1-2), p.268-286
Hauptverfasser:	Démuth, B, Nagy, Z K, Balogh, A, Vigh, T, Marosi, G, Verreck, G, Van Assche, I, Brewster, M E
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry, Pharmaceutical Drug Compounding - methods Polymers - chemistry Rheology Tablets - chemistry
Online-Zugang:	Volltext
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