DNA double strand breaks in human spermatozoa can be predictive for assisted reproductive outcome

Abstract Sperm DNA status has been reported to predict fertility outcomes in infertile men. The terminal deoxynucleotidyl transferase-mediated dUDP nick-end labelling test (TUNEL) is the most widely used method to evaluate this; however, its prognostic value is still debated. One hundred infertile m...

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Veröffentlicht in:	Reproductive biomedicine online 2015-07, Vol.31 (1), p.100-107
Hauptverfasser:	Garolla, Andrea, Cosci, Ilaria, Bertoldo, Alessandro, Sartini, Barbara, Boudjema, Erbeha, Foresta, Carlo
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA Breaks, Double-Stranded DNA Damage double strand breaks Humans ICSI outcome In Situ Nick-End Labeling Infertility, Male - genetics Infertility, Male - therapy Male male infertility Obstetrics and Gynecology Semen Analysis sperm DNA fragmentation Sperm Injections, Intracytoplasmic Treatment Outcome γH2AX
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