Impact of Oral Commensal Bacteria on Degradation of Periodontal Connective Tissue in Mice

Background: Innate and adaptive immunosurveillance mechanisms in response to the normal commensal bacteria can affect periodontal innate defense status. However, it is still unclear how commensal bacteria contribute to the inflammatory responses of junctional epithelium (JE) and periodontal connecti...

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Veröffentlicht in:	Journal of periodontology (1970) 2015-07, Vol.86 (7), p.899-905
Hauptverfasser:	Irie, Koichiro, Tomofuji, Takaaki, Ekuni, Daisuke, Morita, Manabu, Shimazaki, Yoshihiro, Darveau, Richard P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Azo Compounds Bacteria - immunology Cell Movement - immunology Collagen - analysis Collagen - ultrastructure Coloring Agents Connective tissue Connective Tissue - immunology Connective Tissue - microbiology Dentistry Epithelial Attachment - immunology Epithelial Attachment - microbiology Germ-Free Life immunity, innate Immunity, Innate - immunology inflammation Intercellular Adhesion Molecule-1 - analysis Matrix Metalloproteinase 13 - analysis Matrix Metalloproteinase 8 - analysis Mice Microscopy, Polarization - methods Mouth - microbiology Neutrophils - immunology periodontitis Periodontium - immunology Periodontium - microbiology Receptor, Fibroblast Growth Factor, Type 1 - analysis Specific Pathogen-Free Organisms Symbiosis - immunology
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