Lung injury following exposure of rats to relatively high mass concentrations of nitrogen dioxide

Human inhalation exposures to relatively high mass concentrations of the oxidant gas nitrogen dioxide (NO 2) can result in a variety of pulmonary disorders, including life-threatening pulmonary edema, pneumonia, and bronchiolitis obliterans. Inasmuch as most experimental studies to date have examine...

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Veröffentlicht in:	Toxicology (Amsterdam) 1994-05, Vol.89 (3), p.239-277
Hauptverfasser:	Lehnert, B.E., Archuleta, D.C., Ellis, T., Session, W.S., Lehnert, N.M., Gurley, L.R., Stavert, D.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute lung injury Administration, Inhalation Animals Biological and medical sciences Brochoalveolar lavage Chemical and industrial products toxicology. Toxic occupational diseases Disease Models, Animal Dose-Response Relationship, Drug Exercise Gas, fumes Lung Diseases - chemically induced Lung Diseases - metabolism Lung Diseases - prevention & control Male Medical sciences Nitrogen dioxide Nitrogen Dioxide - pharmacokinetics Nitrogen Dioxide - toxicity Permeability - drug effects Physical Conditioning, Animal Pneumonia - chemically induced Pneumonia - pathology Pulmonary Alveoli - pathology Pulmonary edema Pulmonary Edema - chemically induced Pulmonary Edema - metabolism Pulmonary Edema - prevention & control Rats Rats, Inbred F344 Respiration - physiology Taurine Taurine - therapeutic use Time Factors Toxicology Ventilation
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