The HIV care continuum in Latin America: challenges and opportunities
Summary Combination antiretroviral therapy (ART), also known as highly active antiretroviral therapy, provides clinical and immunological benefits for people living with HIV and is an effective strategy to prevent HIV transmission at the individual level. Early initiation of ART as part of a test an...
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Veröffentlicht in: | The Lancet infectious diseases 2015-07, Vol.15 (7), p.833-839 |
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creator | Piñeirúa, Alicia, MD Sierra-Madero, Juan, MD Cahn, Pedro, MD Guevara Palmero, Rafael Napoleón, MD Martínez Buitrago, Ernesto, MD Young, Benjamin, Dr Del Rio, Carlos, Prof |
description | Summary Combination antiretroviral therapy (ART), also known as highly active antiretroviral therapy, provides clinical and immunological benefits for people living with HIV and is an effective strategy to prevent HIV transmission at the individual level. Early initiation of ART as part of a test and treat approach might decrease HIV transmission at the population level, but to do so the HIV continuum of care, from diagnosis to viral suppression, should be optimised. Access to ART has improved greatly in Latin America, and about 600 000 people are on treatment. However, health-care systems are deficient in different stages of the HIV continuum of care, and in some cases only a small proportion of individuals achieve the desired outcome of virological suppression. At present, data for most Latin American countries are not sufficient to build reliable metrics. Available data and estimates show that many people living with HIV in Latin America are unaware of their status, are diagnosed late, and enter into care late. Stigma, administrative barriers, and economic limitations seem to be important determinants of late diagnosis and failure to be linked to and retained in care. Policy makers need reliable data to optimise the HIV care continuum and improve individual-based and population-based outcomes of ART in Latin America. |
doi_str_mv | 10.1016/S1473-3099(15)00108-5 |
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Early initiation of ART as part of a test and treat approach might decrease HIV transmission at the population level, but to do so the HIV continuum of care, from diagnosis to viral suppression, should be optimised. Access to ART has improved greatly in Latin America, and about 600 000 people are on treatment. However, health-care systems are deficient in different stages of the HIV continuum of care, and in some cases only a small proportion of individuals achieve the desired outcome of virological suppression. At present, data for most Latin American countries are not sufficient to build reliable metrics. Available data and estimates show that many people living with HIV in Latin America are unaware of their status, are diagnosed late, and enter into care late. Stigma, administrative barriers, and economic limitations seem to be important determinants of late diagnosis and failure to be linked to and retained in care. Policy makers need reliable data to optimise the HIV care continuum and improve individual-based and population-based outcomes of ART in Latin America.</description><identifier>ISSN: 1473-3099</identifier><identifier>EISSN: 1474-4457</identifier><identifier>DOI: 10.1016/S1473-3099(15)00108-5</identifier><identifier>PMID: 26122456</identifier><identifier>CODEN: LANCAO</identifier><language>eng</language><publisher>United States: Elsevier Ltd</publisher><subject>Acquired immune deficiency syndrome ; AIDS ; Antiretroviral agents ; Antiretroviral drugs ; Antiretroviral Therapy, Highly Active ; CD4 Lymphocyte Count ; Continuity of Patient Care ; Disease transmission ; Drug therapy ; Early Diagnosis ; Epidemics ; HIV ; HIV Infections - diagnosis ; HIV Infections - drug therapy ; HIV Infections - epidemiology ; HIV Infections - immunology ; Human immunodeficiency virus ; Humans ; Infectious Disease ; Infectious diseases ; Latin America - epidemiology ; Medical tests ; Prenatal care ; Prevalence ; Viral Load ; Womens health</subject><ispartof>The Lancet infectious diseases, 2015-07, Vol.15 (7), p.833-839</ispartof><rights>Elsevier Ltd</rights><rights>2015 Elsevier Ltd</rights><rights>Copyright © 2015 Elsevier Ltd. All rights reserved.</rights><rights>Copyright Elsevier Limited Jul 2015</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c448t-4000d2b029e57a45ded4bede2ea37dfe2eb13f0523c0f1dab2cd28519809afe93</citedby><cites>FETCH-LOGICAL-c448t-4000d2b029e57a45ded4bede2ea37dfe2eb13f0523c0f1dab2cd28519809afe93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1473309915001085$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26122456$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Piñeirúa, Alicia, MD</creatorcontrib><creatorcontrib>Sierra-Madero, Juan, MD</creatorcontrib><creatorcontrib>Cahn, Pedro, MD</creatorcontrib><creatorcontrib>Guevara Palmero, Rafael Napoleón, MD</creatorcontrib><creatorcontrib>Martínez Buitrago, Ernesto, MD</creatorcontrib><creatorcontrib>Young, Benjamin, Dr</creatorcontrib><creatorcontrib>Del Rio, Carlos, Prof</creatorcontrib><title>The HIV care continuum in Latin America: challenges and opportunities</title><title>The Lancet infectious diseases</title><addtitle>Lancet Infect Dis</addtitle><description>Summary Combination antiretroviral therapy (ART), also known as highly active antiretroviral therapy, provides clinical and immunological benefits for people living with HIV and is an effective strategy to prevent HIV transmission at the individual level. Early initiation of ART as part of a test and treat approach might decrease HIV transmission at the population level, but to do so the HIV continuum of care, from diagnosis to viral suppression, should be optimised. Access to ART has improved greatly in Latin America, and about 600 000 people are on treatment. However, health-care systems are deficient in different stages of the HIV continuum of care, and in some cases only a small proportion of individuals achieve the desired outcome of virological suppression. At present, data for most Latin American countries are not sufficient to build reliable metrics. Available data and estimates show that many people living with HIV in Latin America are unaware of their status, are diagnosed late, and enter into care late. Stigma, administrative barriers, and economic limitations seem to be important determinants of late diagnosis and failure to be linked to and retained in care. Policy makers need reliable data to optimise the HIV care continuum and improve individual-based and population-based outcomes of ART in Latin America.</description><subject>Acquired immune deficiency syndrome</subject><subject>AIDS</subject><subject>Antiretroviral agents</subject><subject>Antiretroviral drugs</subject><subject>Antiretroviral Therapy, Highly Active</subject><subject>CD4 Lymphocyte Count</subject><subject>Continuity of Patient Care</subject><subject>Disease transmission</subject><subject>Drug therapy</subject><subject>Early Diagnosis</subject><subject>Epidemics</subject><subject>HIV</subject><subject>HIV Infections - diagnosis</subject><subject>HIV Infections - drug therapy</subject><subject>HIV Infections - epidemiology</subject><subject>HIV Infections - immunology</subject><subject>Human immunodeficiency virus</subject><subject>Humans</subject><subject>Infectious Disease</subject><subject>Infectious diseases</subject><subject>Latin America - epidemiology</subject><subject>Medical tests</subject><subject>Prenatal care</subject><subject>Prevalence</subject><subject>Viral Load</subject><subject>Womens health</subject><issn>1473-3099</issn><issn>1474-4457</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkUtP3TAQRq2qqDx_QitL3cAiMHbs5IZFK4R4SVfqosDWcuxJMSTOxU6Q-Pc4NxQkNqxmZJ05Hn8m5DuDQwasOPrLRJlnOVTVPpMHAAwWmfxCttKxyISQ5dd1PyObZDvG-wSVDMQ3sskLxrmQxRY5u75Denl1S40OSE3vB-fHsaPO06VOPT3pMDijj6m5022L_h9Gqr2l_WrVh2H0bnAYd8lGo9uIe691h9ycn12fXmbLPxdXpyfLzAixGDIBAJbXwCuUpRbSohU1WuSo89I2qdYsb0Dy3EDDrK65sXwhWbWASjdY5Ttkf_auQv84YhxU56LBttUe-zEqVlS8lKKACf35Ab3vx-DTdhMFPC-LkiVKzpQJfYwBG7UKrtPhWTFQU85qnbOaQlRMqnXOSqa5H6_2se7Qvk39DzYBv2cAUxxPDoOKxqE3aF1AMyjbu0-v-PXBYFrn01e0D_iM8f01KnIFs2RyMLk2yPwFCSOgQQ</recordid><startdate>20150701</startdate><enddate>20150701</enddate><creator>Piñeirúa, Alicia, MD</creator><creator>Sierra-Madero, Juan, MD</creator><creator>Cahn, Pedro, MD</creator><creator>Guevara Palmero, Rafael Napoleón, MD</creator><creator>Martínez Buitrago, Ernesto, MD</creator><creator>Young, Benjamin, Dr</creator><creator>Del Rio, Carlos, Prof</creator><general>Elsevier Ltd</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>3V.</scope><scope>7QL</scope><scope>7RV</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8C2</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope></search><sort><creationdate>20150701</creationdate><title>The HIV care continuum in Latin America: challenges and opportunities</title><author>Piñeirúa, Alicia, MD ; Sierra-Madero, Juan, MD ; Cahn, Pedro, MD ; Guevara Palmero, Rafael Napoleón, MD ; Martínez Buitrago, Ernesto, MD ; Young, Benjamin, Dr ; Del Rio, Carlos, Prof</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c448t-4000d2b029e57a45ded4bede2ea37dfe2eb13f0523c0f1dab2cd28519809afe93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Acquired immune deficiency syndrome</topic><topic>AIDS</topic><topic>Antiretroviral agents</topic><topic>Antiretroviral drugs</topic><topic>Antiretroviral Therapy, Highly Active</topic><topic>CD4 Lymphocyte Count</topic><topic>Continuity of Patient Care</topic><topic>Disease transmission</topic><topic>Drug therapy</topic><topic>Early Diagnosis</topic><topic>Epidemics</topic><topic>HIV</topic><topic>HIV Infections - 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Academic</collection><jtitle>The Lancet infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Piñeirúa, Alicia, MD</au><au>Sierra-Madero, Juan, MD</au><au>Cahn, Pedro, MD</au><au>Guevara Palmero, Rafael Napoleón, MD</au><au>Martínez Buitrago, Ernesto, MD</au><au>Young, Benjamin, Dr</au><au>Del Rio, Carlos, Prof</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The HIV care continuum in Latin America: challenges and opportunities</atitle><jtitle>The Lancet infectious diseases</jtitle><addtitle>Lancet Infect Dis</addtitle><date>2015-07-01</date><risdate>2015</risdate><volume>15</volume><issue>7</issue><spage>833</spage><epage>839</epage><pages>833-839</pages><issn>1473-3099</issn><eissn>1474-4457</eissn><coden>LANCAO</coden><abstract>Summary Combination antiretroviral therapy (ART), also known as highly active antiretroviral therapy, provides clinical and immunological benefits for people living with HIV and is an effective strategy to prevent HIV transmission at the individual level. Early initiation of ART as part of a test and treat approach might decrease HIV transmission at the population level, but to do so the HIV continuum of care, from diagnosis to viral suppression, should be optimised. Access to ART has improved greatly in Latin America, and about 600 000 people are on treatment. However, health-care systems are deficient in different stages of the HIV continuum of care, and in some cases only a small proportion of individuals achieve the desired outcome of virological suppression. At present, data for most Latin American countries are not sufficient to build reliable metrics. Available data and estimates show that many people living with HIV in Latin America are unaware of their status, are diagnosed late, and enter into care late. Stigma, administrative barriers, and economic limitations seem to be important determinants of late diagnosis and failure to be linked to and retained in care. Policy makers need reliable data to optimise the HIV care continuum and improve individual-based and population-based outcomes of ART in Latin America.</abstract><cop>United States</cop><pub>Elsevier Ltd</pub><pmid>26122456</pmid><doi>10.1016/S1473-3099(15)00108-5</doi><tpages>7</tpages></addata></record> |
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subjects | Acquired immune deficiency syndrome AIDS Antiretroviral agents Antiretroviral drugs Antiretroviral Therapy, Highly Active CD4 Lymphocyte Count Continuity of Patient Care Disease transmission Drug therapy Early Diagnosis Epidemics HIV HIV Infections - diagnosis HIV Infections - drug therapy HIV Infections - epidemiology HIV Infections - immunology Human immunodeficiency virus Humans Infectious Disease Infectious diseases Latin America - epidemiology Medical tests Prenatal care Prevalence Viral Load Womens health |
title | The HIV care continuum in Latin America: challenges and opportunities |
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