Enhanced early osteogenic differentiation by silicon-substituted hydroxyapatite ceramics fabricated via ultrasonic spray pyrolysis route
The influence of silicon-substituted hydroxyapatite (Si-HAp) on osteogenic differentiation was assessed by biological analysis. Si-HAp was prepared by ultrasonic spray pyrolysis (USSP) technique using various amounts of Si (0, 0.8, and 1.6 mass%). Chemical analysis revealed that Si was incorporated...
Gespeichert in:
| Veröffentlicht in: | Journal of materials science. Materials in medicine 2012-12, Vol.23 (12), p.2923-2932 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2932 |
|---|---|
| container_issue | 12 |
| container_start_page | 2923 |
| container_title | Journal of materials science. Materials in medicine |
| container_volume | 23 |
| creator | Honda, Michiyo Kikushima, Koichi Kawanobe, Yusuke Konishi, Toshiisa Mizumoto, Minori Aizawa, Mamoru |
| description | The influence of silicon-substituted hydroxyapatite (Si-HAp) on osteogenic differentiation was assessed by biological analysis. Si-HAp was prepared by ultrasonic spray pyrolysis (USSP) technique using various amounts of Si (0, 0.8, and 1.6 mass%). Chemical analysis revealed that Si was incorporated into the hydroxyapatite (HAp) lattice with no other crystalline phase and which caused the change of crystal structure. Biological analyses showed that the Si contents affected the cell proliferation and morphology, suggesting that there is an optimal Si content for cell culture. As for differentiation, alkaline phosphatase activity and osteocalcin production of Si-HAp were higher than those of HAp. Gene expression profiles also revealed that substitution of Si (0.8 mass%) up-regulated the expression levels of
osteocalcin
and especially
Runx2
, a master gene for osteoblast development. These results suggest that incorporating Si into the HAp lattice may enhance the bioactivity, particularly during early osteoblast development. |
| doi_str_mv | 10.1007/s10856-012-4744-x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1692397488</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1220570283</sourcerecordid><originalsourceid>FETCH-LOGICAL-c567t-de5580ae1da1ad7389754f5a007afe1c6233615907cddb84e7023f2c1e32ca483</originalsourceid><addsrcrecordid>eNqNkkuLFDEUhYMoTjv6A9xIQAQ3pXlWkqUM4wMG3Og63EqlZjJUV8okJV3_wJ9tim4fCEKvsvnuuSfnHoSeU_KGEqLeZkq0bBtCWSOUEM3hAdpRqXgjNNcP0Y4YqRohOblAT3K-J4QII-VjdMGYNkRSs0M_rqc7mJzvsYc0rjjm4uOtn4LDfRgGn_xUApQQJ9ytOIcxuDg1eelyCWUpde5u7VM8rDBXqnjsfIJ9cBkP0KXgYEO-B8DLWBLkuAnnOcGK5zXFcc0h4xSr0FP0aIAx-2en9xJ9fX_95epjc_P5w6erdzeNk60qTe-l1AQ87YFCr7g2SopBQo0DBk9dyzhvqTREub7vtPCKMD4wRz1nDmoul-j1UXdO8dvic7H7kJ0fR5h8XLKlrWHcKKHPQJmhLVGEkzNQqVTLGWVnoIzI6lrzir78B72PS5pqPJZSo6pJSbbd9Ei5FHNOfrBzCntIq6XEbj2xx57Y2hO79cQe6syLk_LS7X3_e-JXMSrw6gRAdjAOqZYk5D9cqwTTYvsNO3L1qGG69ekvi__d_hPUl9ep</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1197748500</pqid></control><display><type>article</type><title>Enhanced early osteogenic differentiation by silicon-substituted hydroxyapatite ceramics fabricated via ultrasonic spray pyrolysis route</title><source>MEDLINE</source><source>SpringerLink Journals</source><creator>Honda, Michiyo ; Kikushima, Koichi ; Kawanobe, Yusuke ; Konishi, Toshiisa ; Mizumoto, Minori ; Aizawa, Mamoru</creator><creatorcontrib>Honda, Michiyo ; Kikushima, Koichi ; Kawanobe, Yusuke ; Konishi, Toshiisa ; Mizumoto, Minori ; Aizawa, Mamoru</creatorcontrib><description>The influence of silicon-substituted hydroxyapatite (Si-HAp) on osteogenic differentiation was assessed by biological analysis. Si-HAp was prepared by ultrasonic spray pyrolysis (USSP) technique using various amounts of Si (0, 0.8, and 1.6 mass%). Chemical analysis revealed that Si was incorporated into the hydroxyapatite (HAp) lattice with no other crystalline phase and which caused the change of crystal structure. Biological analyses showed that the Si contents affected the cell proliferation and morphology, suggesting that there is an optimal Si content for cell culture. As for differentiation, alkaline phosphatase activity and osteocalcin production of Si-HAp were higher than those of HAp. Gene expression profiles also revealed that substitution of Si (0.8 mass%) up-regulated the expression levels of
osteocalcin
and especially
Runx2
, a master gene for osteoblast development. These results suggest that incorporating Si into the HAp lattice may enhance the bioactivity, particularly during early osteoblast development.</description><identifier>ISSN: 0957-4530</identifier><identifier>EISSN: 1573-4838</identifier><identifier>DOI: 10.1007/s10856-012-4744-x</identifier><identifier>PMID: 22890519</identifier><language>eng</language><publisher>Boston: Springer US</publisher><subject>3T3 Cells ; Alkaline Phosphatase - metabolism ; Animals ; Biocompatibility ; Biological ; Biological and medical sciences ; Biomaterials ; Biomedical Engineering and Bioengineering ; Biomedical materials ; Cell culture ; Cell Culture Techniques - methods ; Cell Differentiation ; Ceramics ; Ceramics - chemistry ; Chemistry and Materials Science ; Composites ; Crystal structure ; Differentiation ; Durapatite - chemistry ; Glass ; Hydroxyapatite ; Materials Science ; Materials Testing ; Medical sciences ; Mice ; Microscopy, Fluorescence - methods ; Natural Materials ; Osteoblasts - metabolism ; Osteocalcin - metabolism ; Osteocytes - cytology ; Osteogenesis ; Polymer Sciences ; Regenerative Medicine/Tissue Engineering ; Silicon ; Silicon - chemistry ; Solvents - chemistry ; Spectroscopy, Fourier Transform Infrared - methods ; Spray pyrolysis ; Surfaces and Interfaces ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Technology. Biomaterials. Equipments ; Temperature ; Thin Films ; Time Factors ; Ultrasonics ; X-Ray Diffraction - methods</subject><ispartof>Journal of materials science. Materials in medicine, 2012-12, Vol.23 (12), p.2923-2932</ispartof><rights>Springer Science+Business Media, LLC 2012</rights><rights>2014 INIST-CNRS</rights><rights>Springer Science+Business Media New York 2012</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c567t-de5580ae1da1ad7389754f5a007afe1c6233615907cddb84e7023f2c1e32ca483</citedby><cites>FETCH-LOGICAL-c567t-de5580ae1da1ad7389754f5a007afe1c6233615907cddb84e7023f2c1e32ca483</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10856-012-4744-x$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10856-012-4744-x$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26742842$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22890519$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Honda, Michiyo</creatorcontrib><creatorcontrib>Kikushima, Koichi</creatorcontrib><creatorcontrib>Kawanobe, Yusuke</creatorcontrib><creatorcontrib>Konishi, Toshiisa</creatorcontrib><creatorcontrib>Mizumoto, Minori</creatorcontrib><creatorcontrib>Aizawa, Mamoru</creatorcontrib><title>Enhanced early osteogenic differentiation by silicon-substituted hydroxyapatite ceramics fabricated via ultrasonic spray pyrolysis route</title><title>Journal of materials science. Materials in medicine</title><addtitle>J Mater Sci: Mater Med</addtitle><addtitle>J Mater Sci Mater Med</addtitle><description>The influence of silicon-substituted hydroxyapatite (Si-HAp) on osteogenic differentiation was assessed by biological analysis. Si-HAp was prepared by ultrasonic spray pyrolysis (USSP) technique using various amounts of Si (0, 0.8, and 1.6 mass%). Chemical analysis revealed that Si was incorporated into the hydroxyapatite (HAp) lattice with no other crystalline phase and which caused the change of crystal structure. Biological analyses showed that the Si contents affected the cell proliferation and morphology, suggesting that there is an optimal Si content for cell culture. As for differentiation, alkaline phosphatase activity and osteocalcin production of Si-HAp were higher than those of HAp. Gene expression profiles also revealed that substitution of Si (0.8 mass%) up-regulated the expression levels of
osteocalcin
and especially
Runx2
, a master gene for osteoblast development. These results suggest that incorporating Si into the HAp lattice may enhance the bioactivity, particularly during early osteoblast development.</description><subject>3T3 Cells</subject><subject>Alkaline Phosphatase - metabolism</subject><subject>Animals</subject><subject>Biocompatibility</subject><subject>Biological</subject><subject>Biological and medical sciences</subject><subject>Biomaterials</subject><subject>Biomedical Engineering and Bioengineering</subject><subject>Biomedical materials</subject><subject>Cell culture</subject><subject>Cell Culture Techniques - methods</subject><subject>Cell Differentiation</subject><subject>Ceramics</subject><subject>Ceramics - chemistry</subject><subject>Chemistry and Materials Science</subject><subject>Composites</subject><subject>Crystal structure</subject><subject>Differentiation</subject><subject>Durapatite - chemistry</subject><subject>Glass</subject><subject>Hydroxyapatite</subject><subject>Materials Science</subject><subject>Materials Testing</subject><subject>Medical sciences</subject><subject>Mice</subject><subject>Microscopy, Fluorescence - methods</subject><subject>Natural Materials</subject><subject>Osteoblasts - metabolism</subject><subject>Osteocalcin - metabolism</subject><subject>Osteocytes - cytology</subject><subject>Osteogenesis</subject><subject>Polymer Sciences</subject><subject>Regenerative Medicine/Tissue Engineering</subject><subject>Silicon</subject><subject>Silicon - chemistry</subject><subject>Solvents - chemistry</subject><subject>Spectroscopy, Fourier Transform Infrared - methods</subject><subject>Spray pyrolysis</subject><subject>Surfaces and Interfaces</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Technology. Biomaterials. Equipments</subject><subject>Temperature</subject><subject>Thin Films</subject><subject>Time Factors</subject><subject>Ultrasonics</subject><subject>X-Ray Diffraction - methods</subject><issn>0957-4530</issn><issn>1573-4838</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqNkkuLFDEUhYMoTjv6A9xIQAQ3pXlWkqUM4wMG3Og63EqlZjJUV8okJV3_wJ9tim4fCEKvsvnuuSfnHoSeU_KGEqLeZkq0bBtCWSOUEM3hAdpRqXgjNNcP0Y4YqRohOblAT3K-J4QII-VjdMGYNkRSs0M_rqc7mJzvsYc0rjjm4uOtn4LDfRgGn_xUApQQJ9ytOIcxuDg1eelyCWUpde5u7VM8rDBXqnjsfIJ9cBkP0KXgYEO-B8DLWBLkuAnnOcGK5zXFcc0h4xSr0FP0aIAx-2en9xJ9fX_95epjc_P5w6erdzeNk60qTe-l1AQ87YFCr7g2SopBQo0DBk9dyzhvqTREub7vtPCKMD4wRz1nDmoul-j1UXdO8dvic7H7kJ0fR5h8XLKlrWHcKKHPQJmhLVGEkzNQqVTLGWVnoIzI6lrzir78B72PS5pqPJZSo6pJSbbd9Ei5FHNOfrBzCntIq6XEbj2xx57Y2hO79cQe6syLk_LS7X3_e-JXMSrw6gRAdjAOqZYk5D9cqwTTYvsNO3L1qGG69ekvi__d_hPUl9ep</recordid><startdate>20121201</startdate><enddate>20121201</enddate><creator>Honda, Michiyo</creator><creator>Kikushima, Koichi</creator><creator>Kawanobe, Yusuke</creator><creator>Konishi, Toshiisa</creator><creator>Mizumoto, Minori</creator><creator>Aizawa, Mamoru</creator><general>Springer US</general><general>Springer</general><general>Springer Nature B.V</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QF</scope><scope>7QO</scope><scope>7QQ</scope><scope>7SC</scope><scope>7SE</scope><scope>7SP</scope><scope>7SR</scope><scope>7TA</scope><scope>7TB</scope><scope>7U5</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AO</scope><scope>8BQ</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>F28</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H8D</scope><scope>H8G</scope><scope>HCIFZ</scope><scope>JG9</scope><scope>JQ2</scope><scope>K9.</scope><scope>KB.</scope><scope>KR7</scope><scope>L7M</scope><scope>LK8</scope><scope>L~C</scope><scope>L~D</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>P64</scope><scope>PDBOC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>S0W</scope><scope>7X8</scope><scope>7QP</scope></search><sort><creationdate>20121201</creationdate><title>Enhanced early osteogenic differentiation by silicon-substituted hydroxyapatite ceramics fabricated via ultrasonic spray pyrolysis route</title><author>Honda, Michiyo ; Kikushima, Koichi ; Kawanobe, Yusuke ; Konishi, Toshiisa ; Mizumoto, Minori ; Aizawa, Mamoru</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c567t-de5580ae1da1ad7389754f5a007afe1c6233615907cddb84e7023f2c1e32ca483</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>3T3 Cells</topic><topic>Alkaline Phosphatase - metabolism</topic><topic>Animals</topic><topic>Biocompatibility</topic><topic>Biological</topic><topic>Biological and medical sciences</topic><topic>Biomaterials</topic><topic>Biomedical Engineering and Bioengineering</topic><topic>Biomedical materials</topic><topic>Cell culture</topic><topic>Cell Culture Techniques - methods</topic><topic>Cell Differentiation</topic><topic>Ceramics</topic><topic>Ceramics - chemistry</topic><topic>Chemistry and Materials Science</topic><topic>Composites</topic><topic>Crystal structure</topic><topic>Differentiation</topic><topic>Durapatite - chemistry</topic><topic>Glass</topic><topic>Hydroxyapatite</topic><topic>Materials Science</topic><topic>Materials Testing</topic><topic>Medical sciences</topic><topic>Mice</topic><topic>Microscopy, Fluorescence - methods</topic><topic>Natural Materials</topic><topic>Osteoblasts - metabolism</topic><topic>Osteocalcin - metabolism</topic><topic>Osteocytes - cytology</topic><topic>Osteogenesis</topic><topic>Polymer Sciences</topic><topic>Regenerative Medicine/Tissue Engineering</topic><topic>Silicon</topic><topic>Silicon - chemistry</topic><topic>Solvents - chemistry</topic><topic>Spectroscopy, Fourier Transform Infrared - methods</topic><topic>Spray pyrolysis</topic><topic>Surfaces and Interfaces</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Technology. Biomaterials. Equipments</topic><topic>Temperature</topic><topic>Thin Films</topic><topic>Time Factors</topic><topic>Ultrasonics</topic><topic>X-Ray Diffraction - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Honda, Michiyo</creatorcontrib><creatorcontrib>Kikushima, Koichi</creatorcontrib><creatorcontrib>Kawanobe, Yusuke</creatorcontrib><creatorcontrib>Konishi, Toshiisa</creatorcontrib><creatorcontrib>Mizumoto, Minori</creatorcontrib><creatorcontrib>Aizawa, Mamoru</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Aluminium Industry Abstracts</collection><collection>Biotechnology Research Abstracts</collection><collection>Ceramic Abstracts</collection><collection>Computer and Information Systems Abstracts</collection><collection>Corrosion Abstracts</collection><collection>Electronics & Communications Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Materials Business File</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Aerospace Database</collection><collection>Copper Technical Reference Library</collection><collection>SciTech Premium Collection</collection><collection>Materials Research Database</collection><collection>ProQuest Computer Science Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Civil Engineering Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>ProQuest Biological Science Collection</collection><collection>Computer and Information Systems Abstracts Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Materials Science Collection</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>DELNET Engineering & Technology Collection</collection><collection>MEDLINE - Academic</collection><collection>Calcium & Calcified Tissue Abstracts</collection><jtitle>Journal of materials science. Materials in medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Honda, Michiyo</au><au>Kikushima, Koichi</au><au>Kawanobe, Yusuke</au><au>Konishi, Toshiisa</au><au>Mizumoto, Minori</au><au>Aizawa, Mamoru</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Enhanced early osteogenic differentiation by silicon-substituted hydroxyapatite ceramics fabricated via ultrasonic spray pyrolysis route</atitle><jtitle>Journal of materials science. Materials in medicine</jtitle><stitle>J Mater Sci: Mater Med</stitle><addtitle>J Mater Sci Mater Med</addtitle><date>2012-12-01</date><risdate>2012</risdate><volume>23</volume><issue>12</issue><spage>2923</spage><epage>2932</epage><pages>2923-2932</pages><issn>0957-4530</issn><eissn>1573-4838</eissn><abstract>The influence of silicon-substituted hydroxyapatite (Si-HAp) on osteogenic differentiation was assessed by biological analysis. Si-HAp was prepared by ultrasonic spray pyrolysis (USSP) technique using various amounts of Si (0, 0.8, and 1.6 mass%). Chemical analysis revealed that Si was incorporated into the hydroxyapatite (HAp) lattice with no other crystalline phase and which caused the change of crystal structure. Biological analyses showed that the Si contents affected the cell proliferation and morphology, suggesting that there is an optimal Si content for cell culture. As for differentiation, alkaline phosphatase activity and osteocalcin production of Si-HAp were higher than those of HAp. Gene expression profiles also revealed that substitution of Si (0.8 mass%) up-regulated the expression levels of
osteocalcin
and especially
Runx2
, a master gene for osteoblast development. These results suggest that incorporating Si into the HAp lattice may enhance the bioactivity, particularly during early osteoblast development.</abstract><cop>Boston</cop><pub>Springer US</pub><pmid>22890519</pmid><doi>10.1007/s10856-012-4744-x</doi><tpages>10</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0957-4530 |
| ispartof | Journal of materials science. Materials in medicine, 2012-12, Vol.23 (12), p.2923-2932 |
| issn | 0957-4530 1573-4838 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1692397488 |
| source | MEDLINE; SpringerLink Journals |
| subjects | 3T3 Cells Alkaline Phosphatase - metabolism Animals Biocompatibility Biological Biological and medical sciences Biomaterials Biomedical Engineering and Bioengineering Biomedical materials Cell culture Cell Culture Techniques - methods Cell Differentiation Ceramics Ceramics - chemistry Chemistry and Materials Science Composites Crystal structure Differentiation Durapatite - chemistry Glass Hydroxyapatite Materials Science Materials Testing Medical sciences Mice Microscopy, Fluorescence - methods Natural Materials Osteoblasts - metabolism Osteocalcin - metabolism Osteocytes - cytology Osteogenesis Polymer Sciences Regenerative Medicine/Tissue Engineering Silicon Silicon - chemistry Solvents - chemistry Spectroscopy, Fourier Transform Infrared - methods Spray pyrolysis Surfaces and Interfaces Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Technology. Biomaterials. Equipments Temperature Thin Films Time Factors Ultrasonics X-Ray Diffraction - methods |
| title | Enhanced early osteogenic differentiation by silicon-substituted hydroxyapatite ceramics fabricated via ultrasonic spray pyrolysis route |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-15T06%3A38%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Enhanced%20early%20osteogenic%20differentiation%20by%20silicon-substituted%20hydroxyapatite%20ceramics%20fabricated%20via%20ultrasonic%20spray%20pyrolysis%20route&rft.jtitle=Journal%20of%20materials%20science.%20Materials%20in%20medicine&rft.au=Honda,%20Michiyo&rft.date=2012-12-01&rft.volume=23&rft.issue=12&rft.spage=2923&rft.epage=2932&rft.pages=2923-2932&rft.issn=0957-4530&rft.eissn=1573-4838&rft_id=info:doi/10.1007/s10856-012-4744-x&rft_dat=%3Cproquest_cross%3E1220570283%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1197748500&rft_id=info:pmid/22890519&rfr_iscdi=true |