Encapsulation of a Low Aqueous Solubility Substance in a Biodegradable Polymer using Supercritical Fluid Extraction of Emulsion

The use of the supercritical fluid extraction of emulsion (SFEE) process for the polymer encapsulation of a low aqueous solubility drug substance was investigated, with focus placed on the carbon dioxide extraction step. The effects of process parameterscopolymer ratio, extraction time, pressure, a...

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Veröffentlicht in:	Industrial & engineering chemistry research 2013-01, Vol.52 (1), p.134-141
Hauptverfasser:	Lin, Candy S, Xu, Jane J, Ng, Ka M, Wibowo, Christianto, Luo, Kathy Q
Format:	Artikel
Sprache:	eng
Schlagworte:	Drug delivery systems Drugs Encapsulation Extraction Ibuprofen Particulate composites Solubility Supercritical fluids
Online-Zugang:	Volltext
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