Antibody-free Detection of Human Chorionic Gonadotropin by Use of Liquid Crystals

Human chorionic gonadotropin (hCG) is an important biomarker for the diagnosis of pregnancy and cancers. In this study, we report an antibody-free and label-free mechanism for detecting hCG. To replace enzyme-labeled antibodies, we use a short oligopeptide as an hCG receptor to bind hCG. The short o...

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Veröffentlicht in:	Analytical chemistry (Washington) 2013-11, Vol.85 (22), p.10710-10716
Hauptverfasser:	Ding, Xiaokang, Yang, Kun-Lin
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Antibodies Binding Binding Sites Biomarkers Chorionic Gonadotropin - analysis Diagnostic systems Female Fluorescent Dyes Human Humans Limit of Detection Liquid crystal polymers Liquid Crystals Medical diagnosis Optical communication Optics Peptide Fragments - analysis Peptide Fragments - metabolism Peptide Library Peptides Pregnancy Signal transduction Surface Plasmon Resonance - methods Symbols
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