Structure-Making Effects of Metal Nanoparticles in Amyloid Peptide Fibrillation

There is growing concern that nanoparticles (NPs) may accelerate amyloid protein aggregation and thus cause amyloid‐related diseases. Here, the potential of silver and gold NPs is explored (diameter 20 nm) on the aggregation of the amyloid peptide sequences NNFGAIL from human islet amyloid polypepti...

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Veröffentlicht in:	Particle & particle systems characterization 2015-05, Vol.32 (5), p.573-582
Hauptverfasser:	Gladytz, Anika, Wagner, Maximilian, Häupl, Tilmann, Elsner, Christian, Abel, Bernd
Format:	Artikel
Sprache:	eng
Schlagworte:	Agglomeration aggregation amyloid Aqueous solutions conformational conversion Diseases Fibrillation Gold Nanoparticles Peptides Prions Proteins Silver
Online-Zugang:	Volltext
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