Characterization and Structure Analysis of Cefodizime Sodium Solvates Crystallized from Water and Ethanol Binary Solvent Mixtures

Only a few studies of heterosolvate are reported in the literature. In this article, heterosolvates of cefodizime sodium were prepared in water/ethanol binary solvent mixtures and characterized. Through thermal analysis and composition determination, we deduced that both water and ethanol molecules...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Industrial & engineering chemistry research 2014-02, Vol.53 (8), p.3373-3377
Hauptverfasser:	Liu, Zengkun, Yin, Qiuxiang, Zhang, Xinwei, Gong, Junbo, Xie, Chuang
Format:	Artikel
Sprache:	eng
Schlagworte:	Crystal lattices Ethanol Ethyl alcohol Forming Raw materials Sodium Solvation Solvents
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

container_end_page	3377
container_issue	8
container_start_page	3373
container_title	Industrial & engineering chemistry research
container_volume	53
creator	Liu, Zengkun Yin, Qiuxiang Zhang, Xinwei Gong, Junbo Xie, Chuang
description	Only a few studies of heterosolvate are reported in the literature. In this article, heterosolvates of cefodizime sodium were prepared in water/ethanol binary solvent mixtures and characterized. Through thermal analysis and composition determination, we deduced that both water and ethanol molecules participated in the forming of crystal lattice. The general chemical name of heterosolvates may be defined as cefodizime sesquihydrate sesquiethanolate. Then, the studies on infrared ATR and Raman spectroscopy provided a strong evidence of intermolecular hydrogen bonds. Further, the crystal structure of solvates was analyzed by the powder X-ray diffraction data. The results indicated that the structure differences between solvate and raw material were mainly caused by the solvent effect, leading to forming solvation through intermolecular hydrogen bonding.
doi_str_mv	10.1021/ie403374q
format	Article
fullrecord	<record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1692327908</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1692327908</sourcerecordid><originalsourceid>FETCH-LOGICAL-a325t-2b677237f2b23f3a1a05e9c0557eff562a322a2cd6426ce4d0b8f2198c2c9013</originalsourceid><addsrcrecordid>eNqFkU1LAzEQhoMoWKsH_0Eugh5W87HZ3RzrUj9A8dCCxyXNJjSS3dgkK7Y3_7lpK54ET-8wPDMv7wwA5xhdY0TwjVE5orTMVwdghBlBGUM5OwQjVFVVxqqKHYOTEN4QQozl-Qh81UvhhYzKm42IxvVQ9C2cRT_IOHgFJ72w62ACdBrWSrvWbEyn4CwVQ5fEfoioAqz9OkRhrdmoFmrvOvia-n63bBqXoncW3ppe-PVuRvURPpvPrUM4BUda2KDOfnQM5nfTef2QPb3cP9aTp0xQwmJGFkVZElpqsiBUU4EFYorLFKNUWrOCJIwIItsiJ4VUeYsWlSaYV5JIjjAdg8v92nfvVoMKselMkMpa0Ss3hAYXnFBSclT9jya3oig45wm92qPSuxC80s27N12K2WDUbB_S_D4ksRd7VsjQvLnBp9OGP7hvRLKLfQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1562666999</pqid></control><display><type>article</type><title>Characterization and Structure Analysis of Cefodizime Sodium Solvates Crystallized from Water and Ethanol Binary Solvent Mixtures</title><source>American Chemical Society Publications</source><creator>Liu, Zengkun ; Yin, Qiuxiang ; Zhang, Xinwei ; Gong, Junbo ; Xie, Chuang</creator><creatorcontrib>Liu, Zengkun ; Yin, Qiuxiang ; Zhang, Xinwei ; Gong, Junbo ; Xie, Chuang</creatorcontrib><description>Only a few studies of heterosolvate are reported in the literature. In this article, heterosolvates of cefodizime sodium were prepared in water/ethanol binary solvent mixtures and characterized. Through thermal analysis and composition determination, we deduced that both water and ethanol molecules participated in the forming of crystal lattice. The general chemical name of heterosolvates may be defined as cefodizime sesquihydrate sesquiethanolate. Then, the studies on infrared ATR and Raman spectroscopy provided a strong evidence of intermolecular hydrogen bonds. Further, the crystal structure of solvates was analyzed by the powder X-ray diffraction data. The results indicated that the structure differences between solvate and raw material were mainly caused by the solvent effect, leading to forming solvation through intermolecular hydrogen bonding.</description><identifier>ISSN: 0888-5885</identifier><identifier>EISSN: 1520-5045</identifier><identifier>DOI: 10.1021/ie403374q</identifier><language>eng</language><publisher>American Chemical Society</publisher><subject>Crystal lattices ; Ethanol ; Ethyl alcohol ; Forming ; Raw materials ; Sodium ; Solvation ; Solvents</subject><ispartof>Industrial & engineering chemistry research, 2014-02, Vol.53 (8), p.3373-3377</ispartof><rights>Copyright © 2014 American Chemical Society</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a325t-2b677237f2b23f3a1a05e9c0557eff562a322a2cd6426ce4d0b8f2198c2c9013</citedby><cites>FETCH-LOGICAL-a325t-2b677237f2b23f3a1a05e9c0557eff562a322a2cd6426ce4d0b8f2198c2c9013</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/ie403374q$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/ie403374q$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>314,777,781,2752,27057,27905,27906,56719,56769</link.rule.ids></links><search><creatorcontrib>Liu, Zengkun</creatorcontrib><creatorcontrib>Yin, Qiuxiang</creatorcontrib><creatorcontrib>Zhang, Xinwei</creatorcontrib><creatorcontrib>Gong, Junbo</creatorcontrib><creatorcontrib>Xie, Chuang</creatorcontrib><title>Characterization and Structure Analysis of Cefodizime Sodium Solvates Crystallized from Water and Ethanol Binary Solvent Mixtures</title><title>Industrial & engineering chemistry research</title><addtitle>Ind. Eng. Chem. Res</addtitle><description>Only a few studies of heterosolvate are reported in the literature. In this article, heterosolvates of cefodizime sodium were prepared in water/ethanol binary solvent mixtures and characterized. Through thermal analysis and composition determination, we deduced that both water and ethanol molecules participated in the forming of crystal lattice. The general chemical name of heterosolvates may be defined as cefodizime sesquihydrate sesquiethanolate. Then, the studies on infrared ATR and Raman spectroscopy provided a strong evidence of intermolecular hydrogen bonds. Further, the crystal structure of solvates was analyzed by the powder X-ray diffraction data. The results indicated that the structure differences between solvate and raw material were mainly caused by the solvent effect, leading to forming solvation through intermolecular hydrogen bonding.</description><subject>Crystal lattices</subject><subject>Ethanol</subject><subject>Ethyl alcohol</subject><subject>Forming</subject><subject>Raw materials</subject><subject>Sodium</subject><subject>Solvation</subject><subject>Solvents</subject><issn>0888-5885</issn><issn>1520-5045</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><recordid>eNqFkU1LAzEQhoMoWKsH_0Eugh5W87HZ3RzrUj9A8dCCxyXNJjSS3dgkK7Y3_7lpK54ET-8wPDMv7wwA5xhdY0TwjVE5orTMVwdghBlBGUM5OwQjVFVVxqqKHYOTEN4QQozl-Qh81UvhhYzKm42IxvVQ9C2cRT_IOHgFJ72w62ACdBrWSrvWbEyn4CwVQ5fEfoioAqz9OkRhrdmoFmrvOvia-n63bBqXoncW3ppe-PVuRvURPpvPrUM4BUda2KDOfnQM5nfTef2QPb3cP9aTp0xQwmJGFkVZElpqsiBUU4EFYorLFKNUWrOCJIwIItsiJ4VUeYsWlSaYV5JIjjAdg8v92nfvVoMKselMkMpa0Ss3hAYXnFBSclT9jya3oig45wm92qPSuxC80s27N12K2WDUbB_S_D4ksRd7VsjQvLnBp9OGP7hvRLKLfQ</recordid><startdate>20140226</startdate><enddate>20140226</enddate><creator>Liu, Zengkun</creator><creator>Yin, Qiuxiang</creator><creator>Zhang, Xinwei</creator><creator>Gong, Junbo</creator><creator>Xie, Chuang</creator><general>American Chemical Society</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7QH</scope><scope>7UA</scope><scope>C1K</scope><scope>7SR</scope><scope>7TB</scope><scope>8BQ</scope><scope>8FD</scope><scope>FR3</scope><scope>JG9</scope></search><sort><creationdate>20140226</creationdate><title>Characterization and Structure Analysis of Cefodizime Sodium Solvates Crystallized from Water and Ethanol Binary Solvent Mixtures</title><author>Liu, Zengkun ; Yin, Qiuxiang ; Zhang, Xinwei ; Gong, Junbo ; Xie, Chuang</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a325t-2b677237f2b23f3a1a05e9c0557eff562a322a2cd6426ce4d0b8f2198c2c9013</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Crystal lattices</topic><topic>Ethanol</topic><topic>Ethyl alcohol</topic><topic>Forming</topic><topic>Raw materials</topic><topic>Sodium</topic><topic>Solvation</topic><topic>Solvents</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Liu, Zengkun</creatorcontrib><creatorcontrib>Yin, Qiuxiang</creatorcontrib><creatorcontrib>Zhang, Xinwei</creatorcontrib><creatorcontrib>Gong, Junbo</creatorcontrib><creatorcontrib>Xie, Chuang</creatorcontrib><collection>CrossRef</collection><collection>Aqualine</collection><collection>Water Resources Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineered Materials Abstracts</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Materials Research Database</collection><jtitle>Industrial & engineering chemistry research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Liu, Zengkun</au><au>Yin, Qiuxiang</au><au>Zhang, Xinwei</au><au>Gong, Junbo</au><au>Xie, Chuang</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Characterization and Structure Analysis of Cefodizime Sodium Solvates Crystallized from Water and Ethanol Binary Solvent Mixtures</atitle><jtitle>Industrial & engineering chemistry research</jtitle><addtitle>Ind. Eng. Chem. Res</addtitle><date>2014-02-26</date><risdate>2014</risdate><volume>53</volume><issue>8</issue><spage>3373</spage><epage>3377</epage><pages>3373-3377</pages><issn>0888-5885</issn><eissn>1520-5045</eissn><abstract>Only a few studies of heterosolvate are reported in the literature. In this article, heterosolvates of cefodizime sodium were prepared in water/ethanol binary solvent mixtures and characterized. Through thermal analysis and composition determination, we deduced that both water and ethanol molecules participated in the forming of crystal lattice. The general chemical name of heterosolvates may be defined as cefodizime sesquihydrate sesquiethanolate. Then, the studies on infrared ATR and Raman spectroscopy provided a strong evidence of intermolecular hydrogen bonds. Further, the crystal structure of solvates was analyzed by the powder X-ray diffraction data. The results indicated that the structure differences between solvate and raw material were mainly caused by the solvent effect, leading to forming solvation through intermolecular hydrogen bonding.</abstract><pub>American Chemical Society</pub><doi>10.1021/ie403374q</doi><tpages>5</tpages></addata></record>
fulltext	fulltext
identifier	ISSN: 0888-5885
ispartof	Industrial & engineering chemistry research, 2014-02, Vol.53 (8), p.3373-3377
issn	0888-5885 1520-5045
language	eng
recordid	cdi_proquest_miscellaneous_1692327908
source	American Chemical Society Publications
subjects	Crystal lattices Ethanol Ethyl alcohol Forming Raw materials Sodium Solvation Solvents
title	Characterization and Structure Analysis of Cefodizime Sodium Solvates Crystallized from Water and Ethanol Binary Solvent Mixtures
url	https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-17T19%3A54%3A38IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Characterization%20and%20Structure%20Analysis%20of%20Cefodizime%20Sodium%20Solvates%20Crystallized%20from%20Water%20and%20Ethanol%20Binary%20Solvent%20Mixtures&rft.jtitle=Industrial%20&%20engineering%20chemistry%20research&rft.au=Liu,%20Zengkun&rft.date=2014-02-26&rft.volume=53&rft.issue=8&rft.spage=3373&rft.epage=3377&rft.pages=3373-3377&rft.issn=0888-5885&rft.eissn=1520-5045&rft_id=info:doi/10.1021/ie403374q&rft_dat=%3Cproquest_cross%3E1692327908%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1562666999&rft_id=info:pmid/&rfr_iscdi=true