Theragnostic pH-Sensitive Gold Nanoparticles for the Selective Surface Enhanced Raman Scattering and Photothermal Cancer Therapy

We report a nanoparticle-based probe that can be used for a “turn-on” theragnostic agent for simultaneous Raman imaging/diagnosis and photothermal therapy. The agent consists of a 10 nm spherical gold nanoparticle (NP) with pH-responsive ligands and Raman probes on the surface. They are engineered t...

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Veröffentlicht in:	Analytical chemistry (Washington) 2013-08, Vol.85 (16), p.7674-7681
Hauptverfasser:	Jung, Sungwook, Nam, Jutaek, Hwang, Sekyu, Park, Joonhyuck, Hur, Jaehyun, Im, Kyuhyun, Park, Nokyoung, Kim, Sungjee
Format:	Artikel
Sprache:	eng
Schlagworte:	Agglomeration Animals Cancer therapies Cell Line, Tumor Fluid mechanics Gold Gold - chemistry Hydrogen-Ion Concentration Hyperthermia, Induced Imaging Ligands Metal Nanoparticles Mice Microscopy, Electron, Transmission Nanoparticles Nanostructure Neoplasms - therapy Photochemistry Phototherapy - methods Scattering Spectrum Analysis, Raman - methods Surface chemistry Surface Properties Symbols Therapy
Online-Zugang:	Volltext
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