Rapid Prototyping of Multichannel Microfluidic Devices for Single-Molecule DNA Curtain Imaging

Single-molecule imaging and manipulation of biochemical reactions continues to reveal numerous biological insights. To facilitate these studies, we have developed and implemented a high-throughput approach to organize and image hundreds of individual DNA molecules at aligned diffusion barriers. None...

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Veröffentlicht in:	Analytical chemistry (Washington) 2014-05, Vol.86 (9), p.4157-4163
Hauptverfasser:	Robison, Aaron D., Finkelstein, Ilya J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Biochemistry Biological Curtains Deoxyribonucleic acid Devices Dimethylpolysiloxanes - chemistry DNA DNA - analysis DNA Primers Imaging Microfluidics Microfluidics - methods Molecular biology Molecules
Online-Zugang:	Volltext
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