μ- Opioid Receptor Gene A118 G Variants and Persistent Pain Symptoms Among Men and Women Experiencing Motor Vehicle Collision

Abstract The μ-opioid receptor 1 (OPRM1) binds endogenous opioids. Increasing evidence suggests that endogenous OPRM1 agonists released at the time of trauma may contribute to the development of posttraumatic musculoskeletal pain (MSP). In this prospective observational study, we evaluated the hypot...

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Veröffentlicht in:	The journal of pain 2015-07, Vol.16 (7), p.637-644
Hauptverfasser:	Linnstaedt, Sarah D, Hu, JunMei, Bortsov, Andrey V, Soward, April C, Swor, Robert, Jones, Jeffrey, Lee, David, Peak, David, Domeier, Robert, Rathlev, Niels, Hendry, Phyllis, McLean, Samuel A
Format:	Artikel
Sprache:	eng
Schlagworte:	A118 G Accidents, Traffic - psychology Adult Analgesics, Opioid - therapeutic use Anesthesia & Perioperative Care Female Genotype Humans Hyperalgesia - chemically induced Hyperalgesia - genetics Male Middle Aged motor vehicle collision Opioid-induced hyperalgesia pain Pain - complications Pain - drug therapy Pain - genetics Pain Measurement Pain Medicine Polymorphism, Single Nucleotide - genetics Receptors, Opioid, mu - genetics Sex Characteristics Stress, Psychological - etiology Stress, Psychological - genetics Young Adult μ-opioid receptor 1
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