Novel cytotoxic topoisomerase II inhibiting pyrroloiminoquinones from Fijian sponges of the genus Zyzzya

The authors present the isolation and characterization of seven novel [natural] pyrroloiminoquinones, the makaluvamines A-F (1-6), makaluvone (7), and the known compounds discorhabdin A (8) and damirone B (9) from the Fijian sponge Zyzzya cf. marsailis. The makaluvamines exhibit potent in vitro cyto...

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Veröffentlicht in:	Journal of the American Chemical Society 1993-03, Vol.115 (5), p.1632-1638
Hauptverfasser:	Radisky, Derek C, Radisky, Evette S, Barrows, Louis R, Copp, Brent R, Kramer, Robert A, Ireland, Chris M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal poisons toxicology. Antivenoms Biological and medical sciences Marine Medical sciences Toxicology
Online-Zugang:	Volltext
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