Upregulation of Caveolin-1 correlate with Akt expression and poor prognosis in NPC patients

Objectives The aim of this study is to investigate the role of Caveolin‐1 (Cav‐1) in nasopharyngeal carcinoma (NPC) progression and correlated with clinical outcomes. Methods We used quantitative real‐time PCR (qPCR) to detect the difference in the expression of mRNA level of Cav‐1 mRNA in NPC, non‐...

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Veröffentlicht in:	The Laryngoscope 2015-07, Vol.125 (7), p.E231-E238
Hauptverfasser:	Wang, Ying-Piao, Lin, Chih-Feng, Tsai, Shu-Chun, Tsai, Ching-Hwa, Yeh, Te-Huei
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Blotting, Western Carcinoma Caveolin 1 - genetics Caveolin-1 Cell Line, Tumor Cell Movement Epstein-Barr virus Female Gene Expression Regulation, Neoplastic - physiology Humans Immunohistochemistry Male Medical prognosis Middle Aged Nasopharyngeal Carcinoma Nasopharyngeal Neoplasms - diagnosis Nasopharyngeal Neoplasms - genetics Oncogene Protein v-akt - genetics PI3K/Akt Prognosis Protein expression Real-Time Polymerase Chain Reaction RNA, Messenger - genetics RNA, Small Interfering Signal Transduction - genetics Up-Regulation Wound Healing Young Adult
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