Silastic with polyacrylic acid filler: swelling properties, biocompatibility and potential use in cochlear implants

We present a new hygroscopic implant material which consists of high-molecular-weight polyacrylic acid (PAA) as a filler in a Silastic R matrix. The mixture swells upon immersion in bodily fluids; the degree of swelling depends on the ratio of PAA to Silastic and allows the design of implants that w...

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Veröffentlicht in:	Biomaterials 1994-11, Vol.15 (14), p.1161-1169
Hauptverfasser:	Seldon, H.L., Dahm, M.C., Clark, G.M., Crowe, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrylic Resins - adverse effects Acrylic Resins - chemistry Analysis of Variance Animals Biocompatible Materials - chemistry Biological and medical sciences Body Fluids - metabolism Cats Cells, Cultured Cochlea - drug effects Cochlea - pathology Cochlea - ultrastructure Cochlear implant Cochlear Implants Humans hydrogel implant material Macrophages - cytology Macrophages - drug effects Macrophages - ultrastructure Medical sciences Microelectrodes Microscopy, Electron, Scanning Molecular Weight Orthopedic surgery Regression Analysis Silicone Elastomers - adverse effects Silicone Elastomers - chemistry Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
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