Regulation of DNA methylation dictates Cd4 expression during the development of helper and cytotoxic T cell lineages

Cd4 expression in helper and cytotoxic T cells is locked in by gene-expression programs that define lineage identity. Littman and colleagues define stage-specific methylation and demethylation events that regulate the heritable expression of Cd4 . During development, progenitor cells with binary pot...

Ausführliche Beschreibung