The ZNF304-integrin axis protects against anoikis in cancer

Ovarian cancer (OC) is a highly metastatic disease, but no effective strategies to target this process are currently available. Here, an integrative computational analysis of the Cancer Genome Atlas OC data set and experimental validation identifies a zinc finger transcription factor ZNF304 associat...

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Veröffentlicht in:	Nature communications 2015-06, Vol.6 (1), p.7351-7351, Article 7351
Hauptverfasser:	Aslan, Burcu, Monroig, Paloma, Hsu, Ming-Chuan, Pena, Guillermo Armaiz, Rodriguez-Aguayo, Cristian, Gonzalez-Villasana, Vianey, Rupaimoole, Rajesha, Nagaraja, Archana Sidalaghatta, Mangala, Selanere, Han, Hee-Dong, Yuca, Erkan, Wu, Sherry Y., Ivan, Cristina, Moss, Tyler J., Ram, Prahlad T., Wang, Huamin, Gol-Chambers, Alexandra, Ozkayar, Ozgur, Kanlikilicer, Pinar, Fuentes-Mattei, Enrique, Kahraman, Nermin, Pradeep, Sunila, Ozpolat, Bulent, Tucker, Susan, Hung, Mien-Chie, Baggerly, Keith, Bartholomeusz, Geoffrey, Calin, George, Sood, Anil K., Lopez-Berestein, Gabriel
Format:	Artikel
Sprache:	eng
Schlagworte:	38 59 631/80/82/23 631/80/86 692/699/67/1059/602 692/699/67/1517/1709 82/1 82/80 96 96/106 96/2 96/21 96/31 Anoikis Biology Cancer Carcinoma - metabolism Cell Line, Tumor Cell Movement Cell Proliferation Colorectal cancer Datasets Female Gene Expression Regulation, Neoplastic Gene Silencing Genes Genomes Humanities and Social Sciences Humans Integrin beta Chains - metabolism Kinases Medical prognosis Medical research Medicine Metastasis multidisciplinary Nanoparticles Ovarian cancer Ovarian Neoplasms - metabolism Patients Proteins Science Science (multidisciplinary) Survival Transcription factors Transcription Factors - metabolism Tumors Zinc finger proteins
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