Study of the concordance between p16 immunohistochemistry and HPV-PCR genotyping for the viral diagnosis of oropharyngeal squamous cell carcinoma

Abstract Objective The diagnosis of HPV-related oropharyngeal cancer in clinical practice is based on p16 immunohistochemistry and PCR detection of viral DNA (HPV-PCR). The primary objective of this study was to evaluate the concordance between these 2 diagnostic tests. The secondary objective was t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European annals of otorhinolaryngology, head and neck diseases head and neck diseases, 2015-06, Vol.132 (3), p.135-139
Hauptverfasser:	Fonmarty, D, Cherrière, S, Fleury, H, Eimer, S, Majoufre-Lefebvre, C, Castetbon, V, de Monès, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers, Tumor - genetics Carcinoma, Squamous Cell - diagnosis Carcinoma, Squamous Cell - epidemiology Carcinoma, Squamous Cell - virology Cyclin-Dependent Kinase Inhibitor p16 DNA, Viral - analysis Female France - epidemiology Genotype HPV Human papillomavirus 16 - genetics Human papillomavirus 16 - pathogenicity Human Papillomavirus DNA Tests Humans Immunohistochemistry - methods Male Middle Aged Neoplasm Grading Neoplasm Proteins - genetics Neoplasm Staging Oropharyngeal cancer Oropharyngeal Neoplasms - diagnosis Oropharyngeal Neoplasms - epidemiology Oropharyngeal Neoplasms - virology Otolaryngology P16 Papillomavirus Infections - complications Papillomavirus Infections - diagnosis Papillomavirus Infections - epidemiology Papillomavirus Infections - virology PCR Polymerase Chain Reaction Predictive Value of Tests Prevalence Prognosis Prospective Studies Reproducibility of Results Risk Factors Sensitivity and Specificity
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!