Analysis of lifespan-promoting effect of garlic extract by an integrated metabolo-proteomics approach

The beneficial effects of garlic (Allium sativum) consumption in treating human diseases have been reported worldwide over a long period of human history. The strong antioxidant effect of garlic extract (GE) has also recently been claimed to prevent cancer, thrombus formation, cardiovascular disease...

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Veröffentlicht in:	The Journal of nutritional biochemistry 2015-08, Vol.26 (8), p.808-817
Hauptverfasser:	Huang, Chun-Hao, Hsu, Fang-Yu, Wu, Yuan-Heng, Zhong, Linda, Tseng, Mu-Yun, Kuo, Chao-Jen, Hsu, Ao-Lin, Liang, Shih-Shin, Chiou, Shyh-Horng
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcysteine - metabolism Aging Amino Acid Sequence Animals C. elegans Caenorhabditis elegans - genetics Caenorhabditis elegans Proteins - genetics Caenorhabditis elegans Proteins - metabolism Chromatography, Liquid Cloning, Molecular DAF-16 Down-Regulation Evolution, Molecular Forkhead Transcription Factors - genetics Forkhead Transcription Factors - metabolism Garlic - chemistry Garlic extract Longevity - drug effects Mannose-binding lectin Mannose-Binding Lectin - metabolism Metabolo-proteomics Metabolomics - methods Molecular Sequence Data N-Acetylcysteine Plant Extracts - pharmacology Proteomics - methods Signal Transduction Tandem Mass Spectrometry Up-Regulation Vitellogenins - genetics Vitellogenins - metabolism
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