Excitatory amino acid-induced cytotoxicity in primary cultures of mouse cerebellar granule cells correlates with elevated, sustained c-fos protooncogene expression

An elevated, sustained expression of c-fos mRNA was found in primary cultures of mouse cerebellar granule cells following exposure to toxic concentrations of the excitatory amino acids, L-glutamate, L-homocysteate, S-sulpho-L-cysteine and N-methyl-D-aspartate (NMDA), using leakage of lactate dehydro...

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Veröffentlicht in:Neuroscience letters 1995-05, Vol.191 (1-2), p.116-120
Hauptverfasser: Gorman, A M, Scott, M P, Rumsby, P C, Meredith, C, Griffiths, R
Format: Artikel
Sprache:eng
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