Differential expression of transporters for norepinephrine and glutamate in wild type, variant, and WNT1-expressing PC12 cells

Wild type PC12 pheochromocytoma cells express a Na(+)-dependent norepinephrine transporter that operates in the uptake of catecholamines, including dopamine. This transporter is not expressed in two spontaneously occurring flat cell variants of PC12 or in two other flat cell variants whose phenotype...

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Veröffentlicht in:	The Journal of biological chemistry 1993-11, Vol.268 (32), p.23891-23897
Hauptverfasser:	BASKARAN RAMACHANDRAN, HOUBEN, K, ROZENBERG, Y. Y, HAIGH, J. R, VARPETIAN, A, HOWARD, B. D
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine - analogs & derivatives Alanine - pharmacology Amino Acid Sequence Amino Acid Transport System X-AG Analytical, structural and metabolic biochemistry Animals Aspartic Acid - analogs & derivatives Aspartic Acid - metabolism Aspartic Acid - pharmacology Binding and carrier proteins Biological and medical sciences Biological Transport Carrier Proteins - genetics Carrier Proteins - metabolism DNA, Complementary Fundamental and applied biological sciences. Psychology Gene Expression Glycine - metabolism Glycoproteins - genetics Glycoproteins - metabolism Molecular Sequence Data Norepinephrine - metabolism Norepinephrine Plasma Membrane Transport Proteins Oncogene Proteins - biosynthesis Oncogene Proteins - genetics PC12 Cells Phosphonoacetic Acid - analogs & derivatives Phosphonoacetic Acid - pharmacology Proteins RNA, Messenger - metabolism Symporters
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