Reproducible Analysis of Sequencing-Based RNA Structure Probing Data with User-Friendly Tools

RNA structure-probing data can improve the prediction of RNA secondary and tertiary structure and allow structural changes to be identified and investigated. In recent years, massive parallel sequencing has dramatically improved the throughput of RNA structure probing experiments, but at the same ti...

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Veröffentlicht in:	Methods in enzymology 2015, Vol.558, p.153-180
Hauptverfasser:	Kielpinski, Lukasz Jan, Sidiropoulos, Nikolaos, Vinther, Jeppe
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Base Sequence Computational Biology Computer Graphics Data Mining DNA Barcoding, Taxonomic - methods DNA Probes - chemistry Genome High-Throughput Nucleotide Sequencing - instrumentation High-Throughput Nucleotide Sequencing - methods High-Throughput Nucleotide Sequencing - statistics & numerical data Hydroxyl Radical - chemistry Models, Statistical Molecular Probes - chemistry Molecular Sequence Data RNA - chemistry Sequence Analysis, RNA - instrumentation Sequence Analysis, RNA - methods Sequence Analysis, RNA - statistics & numerical data Software
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