Overexpression of neogenin inhibits cell proliferation and induces apoptosis in human MDA-MB-231 breast carcinoma cells

Neogenin has been documented as playing an important role in cancer development. Although an elevated expression of neogenin has been detected in human breast cancer, the role of neogenin in breast cancer cells is not clearly understood. In the present study, we investigated neogenin in breast cance...

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Veröffentlicht in:	Oncology reports 2015-07, Vol.34 (1), p.258-264
Hauptverfasser:	ZHANG, QINGSONG, LIANG, FANG, KE, YANG, HUO, YANPING, LI, MINGCHUANG, LI, YANYAN, YUE, JUNMIN
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Biomarkers, Tumor - biosynthesis Biomarkers, Tumor - genetics Bladder cancer Breast cancer Breast Neoplasms - genetics Breast Neoplasms - pathology Cancer therapies Cell growth Cell Line, Tumor Cell proliferation Cell Proliferation - genetics Cellular proteins Development and progression Female Flow cytometry Gene Expression Regulation, Neoplastic Genetic aspects Humans Kinases Membrane Proteins - biosynthesis Membrane Proteins - genetics migration neogenin Penicillin Phosphorylation Physiology proliferation Properties Signal transduction Studies
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