The Risk of Cancer among Patients with Cystic Fibrosis
Cystic fibrosis is the commonest recessive genetic disease of whites. About 2 to 4 percent of all white persons carry the gene for cystic fibrosis, and there are approximately 25,000 patients with this disease in the United States. 1 The disease has a broad range of symptoms, including meconium ileu...
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| Veröffentlicht in: | The New England journal of medicine 1995-02, Vol.332 (8), p.494-499 |
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| container_title | The New England journal of medicine |
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| creator | Neglia, Joseph P FitzSimmons, Stacey C Maisonneuve, Patrick Schöni, Martin H Schöni-Affolter, Franziska Corey, Mary Lowenfels, Albert B |
| description | Cystic fibrosis is the commonest recessive genetic disease of whites. About 2 to 4 percent of all white persons carry the gene for cystic fibrosis, and there are approximately 25,000 patients with this disease in the United States.
1
The disease has a broad range of symptoms, including meconium ileus, recurrent suppurative lung infection, sinusitis, and pancreatic insufficiency.
Because of improved care, the life span of patients with cystic fibrosis is increasing. In the United States, the median survival of these patients doubled between 1969 and 1990; one third of all patients now attain adulthood.
1
With increasing survival, a predisposition to . . . |
| doi_str_mv | 10.1056/NEJM199502233320803 |
| format | Article |
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1
The disease has a broad range of symptoms, including meconium ileus, recurrent suppurative lung infection, sinusitis, and pancreatic insufficiency.
Because of improved care, the life span of patients with cystic fibrosis is increasing. In the United States, the median survival of these patients doubled between 1969 and 1990; one third of all patients now attain adulthood.
1
With increasing survival, a predisposition to . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJM199502233320803</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>Boston, MA: Massachusetts Medical Society</publisher><subject>Age ; Biological and medical sciences ; Cancer ; Confidence intervals ; Cystic fibrosis ; Epidemiology ; Gastroenterology. Liver. Pancreas. Abdomen ; Gastrointestinal tract ; Genetic disorders ; Health care ; Hospitals ; Liver. Biliary tract. Portal circulation. Exocrine pancreas ; Medical sciences ; Other diseases. Semiology ; Patients ; Physicians ; Preventive medicine ; Statistical analysis ; Tumors ; Womens health</subject><ispartof>The New England journal of medicine, 1995-02, Vol.332 (8), p.494-499</ispartof><rights>Copyright © 1995 Massachusetts Medical Society. All rights reserved.</rights><rights>1995 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c485t-3f0e54252ff454b37eebf31ddba4014989de6c31d451e1884d2b0078cf8296ba3</citedby><cites>FETCH-LOGICAL-c485t-3f0e54252ff454b37eebf31ddba4014989de6c31d451e1884d2b0078cf8296ba3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJM199502233320803$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/1983901756?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,777,781,2746,2747,26084,27905,27906,52363,54045,64364,64366,64368,72218</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3437857$$DView record in Pascal Francis$$Hfree_for_read</backlink></links><search><creatorcontrib>Neglia, Joseph P</creatorcontrib><creatorcontrib>FitzSimmons, Stacey C</creatorcontrib><creatorcontrib>Maisonneuve, Patrick</creatorcontrib><creatorcontrib>Schöni, Martin H</creatorcontrib><creatorcontrib>Schöni-Affolter, Franziska</creatorcontrib><creatorcontrib>Corey, Mary</creatorcontrib><creatorcontrib>Lowenfels, Albert B</creatorcontrib><creatorcontrib>the Cystic Fibrosis and Cancer Study Group</creatorcontrib><title>The Risk of Cancer among Patients with Cystic Fibrosis</title><title>The New England journal of medicine</title><description>Cystic fibrosis is the commonest recessive genetic disease of whites. About 2 to 4 percent of all white persons carry the gene for cystic fibrosis, and there are approximately 25,000 patients with this disease in the United States.
1
The disease has a broad range of symptoms, including meconium ileus, recurrent suppurative lung infection, sinusitis, and pancreatic insufficiency.
Because of improved care, the life span of patients with cystic fibrosis is increasing. In the United States, the median survival of these patients doubled between 1969 and 1990; one third of all patients now attain adulthood.
1
With increasing survival, a predisposition to . . .</description><subject>Age</subject><subject>Biological and medical sciences</subject><subject>Cancer</subject><subject>Confidence intervals</subject><subject>Cystic fibrosis</subject><subject>Epidemiology</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Gastrointestinal tract</subject><subject>Genetic disorders</subject><subject>Health care</subject><subject>Hospitals</subject><subject>Liver. Biliary tract. Portal circulation. Exocrine pancreas</subject><subject>Medical sciences</subject><subject>Other diseases. Semiology</subject><subject>Patients</subject><subject>Physicians</subject><subject>Preventive medicine</subject><subject>Statistical analysis</subject><subject>Tumors</subject><subject>Womens health</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9kElPwzAQhS0EEqXwC7hEgLigwHhL7COKWhaVRaicI8exqUuWEqdC_fe4asUBAXMZafS9NzMPoWMMlxh4cvU4un_AUnIghFJKQADdQQPMKY0Zg2QXDQCIiFkq6T468H4OoTCTA5RMZyZ6cf49am2UqUabLlJ127xFz6p3pul99On6WZStfO90NHZF13rnD9GeVZU3R9s-RK_j0TS7jSdPN3fZ9STWTPA-phYMZ4QTaxlnBU2NKSzFZVkott4vZGkSHQaMY4OFYCUpAFKhrSAyKRQdovON76JrP5bG93ntvDZVpRrTLn2OE5FKCSSAJz_AebvsmnBbHjKRicAAATr9C8JSUAk45Umg6IbS4VXfGZsvOlerbpVjyNdx57_EHVRnW2_ltapsF7J0_ltKGU0FTwN2scHq2ueNmdf_mn4BIyqH9w</recordid><startdate>19950223</startdate><enddate>19950223</enddate><creator>Neglia, Joseph P</creator><creator>FitzSimmons, Stacey C</creator><creator>Maisonneuve, Patrick</creator><creator>Schöni, Martin H</creator><creator>Schöni-Affolter, Franziska</creator><creator>Corey, Mary</creator><creator>Lowenfels, Albert B</creator><general>Massachusetts Medical Society</general><scope>IQODW</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope></search><sort><creationdate>19950223</creationdate><title>The Risk of Cancer among Patients with Cystic Fibrosis</title><author>Neglia, Joseph P ; FitzSimmons, Stacey C ; Maisonneuve, Patrick ; Schöni, Martin H ; Schöni-Affolter, Franziska ; Corey, Mary ; Lowenfels, Albert B</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c485t-3f0e54252ff454b37eebf31ddba4014989de6c31d451e1884d2b0078cf8296ba3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>Age</topic><topic>Biological and medical sciences</topic><topic>Cancer</topic><topic>Confidence intervals</topic><topic>Cystic fibrosis</topic><topic>Epidemiology</topic><topic>Gastroenterology. Liver. Pancreas. Abdomen</topic><topic>Gastrointestinal tract</topic><topic>Genetic disorders</topic><topic>Health care</topic><topic>Hospitals</topic><topic>Liver. Biliary tract. Portal circulation. Exocrine pancreas</topic><topic>Medical sciences</topic><topic>Other diseases. Semiology</topic><topic>Patients</topic><topic>Physicians</topic><topic>Preventive medicine</topic><topic>Statistical analysis</topic><topic>Tumors</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Neglia, Joseph P</creatorcontrib><creatorcontrib>FitzSimmons, Stacey C</creatorcontrib><creatorcontrib>Maisonneuve, Patrick</creatorcontrib><creatorcontrib>Schöni, Martin H</creatorcontrib><creatorcontrib>Schöni-Affolter, Franziska</creatorcontrib><creatorcontrib>Corey, Mary</creatorcontrib><creatorcontrib>Lowenfels, Albert B</creatorcontrib><creatorcontrib>the Cystic Fibrosis and Cancer Study Group</creatorcontrib><collection>Pascal-Francis</collection><collection>CrossRef</collection><collection>Pharma and Biotech Premium PRO</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>New England Journal of Medicine</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>ProQuest Psychology</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Neglia, Joseph P</au><au>FitzSimmons, Stacey C</au><au>Maisonneuve, Patrick</au><au>Schöni, Martin H</au><au>Schöni-Affolter, Franziska</au><au>Corey, Mary</au><au>Lowenfels, Albert B</au><aucorp>the Cystic Fibrosis and Cancer Study Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Risk of Cancer among Patients with Cystic Fibrosis</atitle><jtitle>The New England journal of medicine</jtitle><date>1995-02-23</date><risdate>1995</risdate><volume>332</volume><issue>8</issue><spage>494</spage><epage>499</epage><pages>494-499</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><coden>NEJMAG</coden><abstract>Cystic fibrosis is the commonest recessive genetic disease of whites. About 2 to 4 percent of all white persons carry the gene for cystic fibrosis, and there are approximately 25,000 patients with this disease in the United States.
1
The disease has a broad range of symptoms, including meconium ileus, recurrent suppurative lung infection, sinusitis, and pancreatic insufficiency.
Because of improved care, the life span of patients with cystic fibrosis is increasing. In the United States, the median survival of these patients doubled between 1969 and 1990; one third of all patients now attain adulthood.
1
With increasing survival, a predisposition to . . .</abstract><cop>Boston, MA</cop><pub>Massachusetts Medical Society</pub><doi>10.1056/NEJM199502233320803</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0028-4793 |
| ispartof | The New England journal of medicine, 1995-02, Vol.332 (8), p.494-499 |
| issn | 0028-4793 1533-4406 |
| language | eng |
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| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; ProQuest Central UK/Ireland; New England Journal of Medicine |
| subjects | Age Biological and medical sciences Cancer Confidence intervals Cystic fibrosis Epidemiology Gastroenterology. Liver. Pancreas. Abdomen Gastrointestinal tract Genetic disorders Health care Hospitals Liver. Biliary tract. Portal circulation. Exocrine pancreas Medical sciences Other diseases. Semiology Patients Physicians Preventive medicine Statistical analysis Tumors Womens health |
| title | The Risk of Cancer among Patients with Cystic Fibrosis |
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